Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person RAC1 GDIs block activation of RAC1

Class:Id	Reaction:9013147
_displayName	RAC1 GDIs block activation of RAC1
_doRelease	TRUE
_timestamp	2021-02-25 16:31:10
authored	[InstanceEdit:9695572] Orlic-Milacic, Marija, 2020-07-14 [InstanceEdit:9695561] Rothfels, Karen, 2020-07-14
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9013146] Orlic-Milacic, Marija, 2017-07-24
edited	[InstanceEdit:9716798] Orlic-Milacic, Marija, 2021-02-25
input	[Complex:5674631] RAC1:GDP [plasma membrane] [Homo sapiens] [DefinedSet:9012837] ARHGDIA,ARHGDIB [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9681554] ARHGDIA: a novel gene implicated in nephrotic syndrome [LiteratureReference:9681573] Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1 [LiteratureReference:9681571] RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG [LiteratureReference:196633] RhoGDIgamma: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas [LiteratureReference:9690966] Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase [LiteratureReference:9690973] Identification of a novel protein with GDP dissociation inhibitor activity for the ras-like proteins CDC42Hs and rac I [LiteratureReference:9690976] Silencing of D4-GDI inhibits growth and invasive behavior in MDA-MB-231 cells by activation of Rac-dependent p38 and JNK signaling
modified	[InstanceEdit:9013167] Orlic-Milacic, Marija, 2017-07-24 [InstanceEdit:9013187] Orlic-Milacic, Marija, 2017-07-24 [InstanceEdit:9026093] Orlic-Milacic, Marija, 2017-10-17 [InstanceEdit:9028492] Orlic-Milacic, Marija, 2017-11-08 [InstanceEdit:9690980] Orlic-Milacic, Marija, 2020-06-08 [InstanceEdit:9697611] Orlic-Milacic, Marija, 2020-08-18 [InstanceEdit:9698215] Orlic-Milacic, Marija, 2020-08-24 [InstanceEdit:9705972] Orlic-Milacic, Marija, 2020-11-03 [InstanceEdit:9714229] Orlic-Milacic, Marija, 2021-02-09 [InstanceEdit:9715101] Orlic-Milacic, Marija, 2021-02-16 [InstanceEdit:9715390] Orlic-Milacic, Marija, 2021-02-17 [InstanceEdit:9716666] Orlic-Milacic, Marija, 2021-02-23 [InstanceEdit:9716668] Orlic-Milacic, Marija, 2021-02-23 [InstanceEdit:9716799] Orlic-Milacic, Marija, 2021-02-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RAC1 GDIs block activation of RAC1
output	[Complex:9013179] RAC1:GDP:RAC1 GDIs [cytosol] [Homo sapiens]
releaseDate	2021-03-23
reviewed	[InstanceEdit:9714226] Fort, Philippe, 2021-02-05
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9013154] R-HSA-9013147.2
summation	[Summation:9690967] The following GDP dissociation inhibitors (GDIs) bind to RAC...
(hasEvent)	[Pathway:9013149] RAC1 GTPase cycle [Homo sapiens] [Pathway:9025112] (NEW)ROCK signaling regulates MRLC phosphorylation [Homo sapiens]
(replacementInstances)	[_Deleted:9768324] Deletion of instance: 194854
[Change default viewing format]

No pathways have been reviewed or authored by RAC1 GDIs block activation of RAC1 (9013147)