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Details on Person RHOB binds effectors at the plasma membrane
Class:Id Reaction:9013024
_displayName RHOB binds effectors at the plasma membrane
_doRelease TRUE
_timestamp 2022-06-10 14:42:05
authored [InstanceEdit:9695572] Orlic-Milacic, Marija, 2020-07-14
compartment [Compartment:70101] cytosol [Compartment:876] plasma membrane
created [InstanceEdit:9013025] Orlic-Milacic, Marija, 2017-07-21
edited [InstanceEdit:9716798] Orlic-Milacic, Marija, 2021-02-25
input [Complex:8981459] RHOB:GTP [plasma membrane] [Homo sapiens] [CandidateSet:9013052] RHOB effectors (plasma membrane) [cytosol] [Homo sapiens]
isChimeric FALSE
literatureReference [LiteratureReference:5627666] The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton [LiteratureReference:5623615] Differential binding of RhoA, RhoB, and RhoC to protein kinase C-related kinase (PRK) isoforms PRK1, PRK2, and PRK3: PRKs have the highest affinity for RhoB [LiteratureReference:5625892] A novel partner for the GTP-bound forms of rho and rac [LiteratureReference:5625916] Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron [LiteratureReference:9679344] Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms [LiteratureReference:5666071] Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets [LiteratureReference:5666179] Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain [LiteratureReference:5665745] Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC [LiteratureReference:9694071] Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration
modified [InstanceEdit:9013057] Orlic-Milacic, Marija, 2017-07-21 [InstanceEdit:9013117] Orlic-Milacic, Marija, 2017-07-23 [InstanceEdit:9690071] Orlic-Milacic, Marija, 2020-05-25 [InstanceEdit:9690072] Orlic-Milacic, Marija, 2020-05-25 [InstanceEdit:9691232] Orlic-Milacic, Marija, 2020-06-10 [InstanceEdit:9694018] Orlic-Milacic, Marija, 2020-07-08 [InstanceEdit:9694081] Orlic-Milacic, Marija, 2020-07-10 [InstanceEdit:9697611] Orlic-Milacic, Marija, 2020-08-18 [InstanceEdit:9698215] Orlic-Milacic, Marija, 2020-08-24 [InstanceEdit:9715101] Orlic-Milacic, Marija, 2021-02-16 [InstanceEdit:9715390] Orlic-Milacic, Marija, 2021-02-17 [InstanceEdit:9716170] Orlic-Milacic, Marija, 2021-02-19 [InstanceEdit:9716668] Orlic-Milacic, Marija, 2021-02-23 [InstanceEdit:9716674] Orlic-Milacic, Marija, 2021-02-23 [InstanceEdit:9716799] Orlic-Milacic, Marija, 2021-02-25 [InstanceEdit:9793326] Orlic-Milacic, Marija, 2022-06-10 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name RHOB binds effectors at the plasma membrane
output [Complex:9013053] RHOB:GTP:cytosolic RHOB effectors [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate 2021-03-23
reviewed [InstanceEdit:9714226] Fort, Philippe, 2021-02-05
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9013028] R-HSA-9013024.3
summation [Summation:9690070] In its GTP bound active form, plasma membrane associated RHO...
(hasEvent) [Pathway:9013026] RHOB GTPase cycle [Homo sapiens]
(replacementInstances) [_Deleted:9716816] Deletion of instance: 194894
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No pathways have been reviewed or authored by RHOB binds effectors at the plasma membrane (9013024)