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Details on Person RHOB binds effectors at the plasma membrane

Class:IdReaction:9013024
_displayNameRHOB binds effectors at the plasma membrane
_doReleaseTRUE
_timestamp2022-06-10 14:42:05
authored[InstanceEdit:9695572] Orlic-Milacic, Marija, 2020-07-14
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:9013025] Orlic-Milacic, Marija, 2017-07-21
edited[InstanceEdit:9716798] Orlic-Milacic, Marija, 2021-02-25
input[Complex:8981459] RHOB:GTP [plasma membrane] [Homo sapiens]
[CandidateSet:9013052] RHOB effectors (plasma membrane) [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5627666] The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton
[LiteratureReference:5623615] Differential binding of RhoA, RhoB, and RhoC to protein kinase C-related kinase (PRK) isoforms PRK1, PRK2, and PRK3: PRKs have the highest affinity for RhoB
[LiteratureReference:5625892] A novel partner for the GTP-bound forms of rho and rac
[LiteratureReference:5625916] Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron
[LiteratureReference:9679344] Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms
[LiteratureReference:5666071] Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets
[LiteratureReference:5666179] Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain
[LiteratureReference:5665745] Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC
[LiteratureReference:9694071] Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration
modified[InstanceEdit:9013057] Orlic-Milacic, Marija, 2017-07-21
[InstanceEdit:9013117] Orlic-Milacic, Marija, 2017-07-23
[InstanceEdit:9690071] Orlic-Milacic, Marija, 2020-05-25
[InstanceEdit:9690072] Orlic-Milacic, Marija, 2020-05-25
[InstanceEdit:9691232] Orlic-Milacic, Marija, 2020-06-10
[InstanceEdit:9694018] Orlic-Milacic, Marija, 2020-07-08
[InstanceEdit:9694081] Orlic-Milacic, Marija, 2020-07-10
[InstanceEdit:9697611] Orlic-Milacic, Marija, 2020-08-18
[InstanceEdit:9698215] Orlic-Milacic, Marija, 2020-08-24
[InstanceEdit:9715101] Orlic-Milacic, Marija, 2021-02-16
[InstanceEdit:9715390] Orlic-Milacic, Marija, 2021-02-17
[InstanceEdit:9716170] Orlic-Milacic, Marija, 2021-02-19
[InstanceEdit:9716668] Orlic-Milacic, Marija, 2021-02-23
[InstanceEdit:9716674] Orlic-Milacic, Marija, 2021-02-23
[InstanceEdit:9716799] Orlic-Milacic, Marija, 2021-02-25
[InstanceEdit:9793326] Orlic-Milacic, Marija, 2022-06-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRHOB binds effectors at the plasma membrane
output[Complex:9013053] RHOB:GTP:cytosolic RHOB effectors [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2021-03-23
reviewed[InstanceEdit:9714226] Fort, Philippe, 2021-02-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9013028] R-HSA-9013024.3
summation[Summation:9690070] In its GTP bound active form, plasma membrane associated RHO...
(hasEvent)[Pathway:9013026] RHOB GTPase cycle [Homo sapiens]
(replacementInstances)[_Deleted:9716816] Deletion of instance: 194894
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No pathways have been reviewed or authored by RHOB binds effectors at the plasma membrane (9013024)