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Details on Person phospho-Epor:phospho-Jak2:Lyn:Irs2 binds Stat5

Class:Id	Reaction:9012656
_displayName	phospho-Epor:phospho-Jak2:Lyn:Irs2 binds Stat5
_doRelease	TRUE
_timestamp	2018-08-14 15:55:59
authored	[InstanceEdit:9009422] May, Bruce, 2017-06-17
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9012655] May, Bruce, 2017-07-17
edited	[InstanceEdit:9009422] May, Bruce, 2017-06-17
input	[Complex:9006303] Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2 [plasma membrane] [Mus musculus] [DefinedSet:1168905] Stat5 [cytosol] [Mus musculus] [DefinedSet:1168905] Stat5 [cytosol] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9027157] The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation [LiteratureReference:9027126] Physical and functional interactions between Stat5 and the tyrosine-phosphorylated receptors for erythropoietin and interleukin-3 [LiteratureReference:9006226] Association of JAK2 and STAT5 with erythropoietin receptors. Role of receptor phosphorylation in erythropoietin signal transduction [LiteratureReference:9027158] Identification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activation [LiteratureReference:9027207] Activation of STAT5 during EPO-directed suppression of apoptosis [LiteratureReference:9027156] A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: implications for the docking model of STAT activation [LiteratureReference:9027151] STAT5 activation correlates with erythropoietin receptor-mediated erythroid differentiation of an erythroleukemia cell line
modified	[InstanceEdit:9027297] May, Bruce, 2017-10-29 [InstanceEdit:9027444] May, Bruce, 2017-11-01 [InstanceEdit:9030341] May, Bruce, 2017-11-27 [InstanceEdit:9616794] Matthews, Lisa, 2018-08-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	phospho-Epor:phospho-Jak2:Lyn:Irs2 binds Stat5
output	[Complex:9012642] Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:Stat5 [plasma membrane] [Mus musculus]
releaseDate	2018-09-12
reviewed	[InstanceEdit:9616793] McGraw, Kathy L, 2018-08-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9012665] R-MMU-9012656.2
summation	[Summation:9030339] Stat5 (Stat5a or Stat5b) binds the phosphorylated cytoplasmi...
(inferredFrom)	[Reaction:9012654] EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds STAT5 [Homo sapiens]
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No pathways have been reviewed or authored by phospho-Epor:phospho-Jak2:Lyn:Irs2 binds Stat5 (9012656)