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Details on Person IL18-2 binds 2x(CASP1(120-197):CASP1(317-404))

Class:Id	BlackBoxEvent:9012520
_displayName	IL18-2 binds 2x(CASP1(120-197):CASP1(317-404))
_doRelease	FALSE
_timestamp	2017-11-01 16:15:07
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9012524] Duenas, Corina, 2017-07-14
input	[Complex:448691] Caspase-1 tetramer [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9012551] IL18-2 [cytosol] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:9012590] Duenas, Corina, 2017-07-17 [InstanceEdit:9012846] Duenas, Corina, 2017-07-20 [InstanceEdit:9014804] Varusai, Thawfeek, 2017-08-04 [InstanceEdit:9024301] Duenas, Corina, 2017-10-03 [InstanceEdit:9027447] Jupe, Steve, 2017-11-01
name	IL18-2 binds 2x(CASP1(120-197):CASP1(317-404)) pre-IL18 isoform alpha binds active Caspase-1 tetramer IL18s binds active Caspase-1
output	[Complex:9012506] IL18-2:2x(CASP1(120-197):CASP1(317-404)) [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9012092] IL18 and IL18 propeptide dissociate from Caspase-1 tetramer [Homo sapiens] [Reaction:9012499] IL18(1-193) is cleaved by Caspase-1 active tetramer:IL18(1-193) complex [Homo sapiens] [BlackBoxEvent:9012689] IL37(1-?) and IL37 (?-) dissocates from IL37(1-?):IL37(?-218):CASP1(120-197):CASP1(317-404) [Homo sapiens] [BlackBoxEvent:9012556] IL37:2x(CASP1(120-197):CASP1(317-404)) cleaves IL37 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9012526] R-HSA-9012520.1
summation	[Summation:9012547] Interleukin-18 isoform 2 (IL18-2 or pre-IL18 alpha isoform) ...
(precedingEvent)	[BlackBoxEvent:9012515] IL18-2:2x(CASP1(120-197):CASP1(317-404)) cleaves IL18-2 [Homo sapiens]
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No pathways have been reviewed or authored by IL18-2 binds 2x(CASP1(120-197):CASP1(317-404)) (9012520)