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Details on Person IL18-2(1-36) and IL18-2(37-189) dissociates from IL18-2(1-36):IL18-2(37-189):2x(CASP1(120-197):CASP1(317-404))

Class:Id	BlackBoxEvent:9012500
_displayName	IL18-2(1-36) and IL18-2(37-189) dissociates from IL18-2(1-36):IL18-2(37-189):2x(CASP1(120-197):CASP1(317-404))
_doRelease	FALSE
_timestamp	2017-10-03 10:13:09
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9012524] Duenas, Corina, 2017-07-14
input	[Complex:9012502] IL18-2(1-36):IL18-2(37-189):2x(CASP1(120-197):CASP1(317-404)) [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:448676] A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
modified	[InstanceEdit:9012590] Duenas, Corina, 2017-07-17 [InstanceEdit:9012702] Duenas, Corina, 2017-07-18 [InstanceEdit:9012846] Duenas, Corina, 2017-07-20 [InstanceEdit:9012869] Duenas, Corina, 2017-07-20 [InstanceEdit:9014804] Varusai, Thawfeek, 2017-08-04 [InstanceEdit:9024301] Duenas, Corina, 2017-10-03
name	IL18-2(1-36) and IL18-2(37-189) dissociates from IL18-2(1-36):IL18-2(37-189):2x(CASP1(120-197):CASP1(317-404))
output	[Complex:448691] Caspase-1 tetramer [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:449062] IL18(1-36) [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9012566] IL18-2(37-189) [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9012515] IL18-2:2x(CASP1(120-197):CASP1(317-404)) cleaves IL18-2 [Homo sapiens] [BlackBoxEvent:9012520] IL18-2 binds 2x(CASP1(120-197):CASP1(317-404)) [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9012529] R-HSA-9012500.1
summation	[Summation:9012697] Interleukin-18-2 (37-189) (Conti et al. 1997) and IL18 (1-36...
(precedingEvent)	[BlackBoxEvent:9012521] IL18-2(37-189) translocates from cytosol to the extracellular region [Homo sapiens] [BlackBoxEvent:9012542] IL37 binds 2x(CASP1(120-197):CASP1(317-404)) [Homo sapiens]
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No pathways have been reviewed or authored by IL18-2(1-36) and IL18-2(37-189) dissociates from IL18-2(1-36):IL18-2(37-189):2x(CASP1(120-197):CASP1(317-404)) (9012500)