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Details on Person The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity

Class:Id	LiteratureReference:9012236
_displayName	The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity
_timestamp	2017-07-12 05:42:59
author	[Person:9012241] Lohöfener, Jan [Person:9012237] Steinke, Nicola [Person:9012231] Kay-Fedorov, Penelope [Person:9012234] Baruch, Petra [Person:9012233] Nikulin, Alexey [Person:9012232] Tishchenko, Svetlana [Person:9012244] Manstein, Dietmar J [Person:9012243] Fedorov, Roman
created	[InstanceEdit:9012242] Shamovsky, Veronica, 2017-07-12
journal	Structure
pages	851-62
pubMedIdentifier	25892109
title	The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity
volume	23
year	2015
(literatureReference)	[Summation:8983710] In the cytosol, human 2′-5′-oligoadenylate synthetase 1 (OAS... [Summation:9012240] When bound to viral double-stranded RNA (dsRNA), cytosolic 2... [Summation:9977694] Oligoadenylate synthetase 1 (OAS1) produces the second me... [Summation:9985825] During severe acute respiratory syndrome coronavirus 2 (SARS... [Summation:9985837] When bound to viral double-stranded RNA (dsRNA), 2′-5′-oligo... [Summation:9985884] During infection, particularly with positive-sense RNA virus... [Polymerisation:8983680] OAS1 produces oligoadenylates [Homo sapiens] [Reaction:9985802] SARS-CoV-2 dsRNA-bound GGC-OAS1 produces 2'-5' oligoadenylates [Homo sapiens]
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