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Details on Person CHD1 translation is negatively regulated by miR-26A and B

Class:Id	BlackBoxEvent:9012186
_displayName	CHD1 translation is negatively regulated by miR-26A and B
_doRelease	TRUE
_timestamp	2018-02-23 13:08:25
authored	[InstanceEdit:9024061] Rothfels, Karen, 2017-09-29
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9012188] Rothfels, Karen, 2017-07-11
edited	[InstanceEdit:9028899] Rothfels, Karen, 2017-11-13
input	[EntityWithAccessionedSequence:9012181] CHD1 mRNA [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9012130] Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2
modified	[InstanceEdit:9024070] Rothfels, Karen, 2017-09-29 [InstanceEdit:9028380] Rothfels, Karen, 2017-11-07 [InstanceEdit:9028902] Rothfels, Karen, 2017-11-13 [InstanceEdit:9029181] Rothfels, Karen, 2017-11-14 [InstanceEdit:9038171] Rothfels, Karen, 2018-02-23 [InstanceEdit:9038275] Rothfels, Karen, 2018-02-23 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CHD1 translation is negatively regulated by miR-26A and B
output	[EntityWithAccessionedSequence:9012174] CHD1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9011958] miR-26A and B bind to the 3'UTR of the GREB1 mRNA [Homo sapiens] [BlackBoxEvent:9011950] Estrogen-responsive GREB1 gene transcription [Homo sapiens] [BlackBoxEvent:9011950] Estrogen-responsive GREB1 gene transcription [Homo sapiens] [BlackBoxEvent:9012000] NR5A2, ZNF217 and NCOA3 bind GREB1 promoter [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:9012221] Negative gene expression regulation by 'CHD1 mRNA:mIR-26 RISC [cytosol]'
releaseDate	2018-03-21
reviewed	[InstanceEdit:9038169] Magnani, Luca, 2018-02-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9012189] R-HSA-9012186.3
summation	[Summation:9012187] Translation of CHD1 is negatively regulated by binding of mI...
(hasEvent)	[Pathway:9018519] Estrogen-dependent gene expression [Homo sapiens]
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No pathways have been reviewed or authored by CHD1 translation is negatively regulated by miR-26A and B (9012186)