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Details on Person ESR1:ESTG, JUND:FOSB and Cohesin Complex bind distal enhancer elements in MYC gene promoter
Class:Id Reaction:9011997 _displayName ESR1:ESTG, JUND:FOSB and Cohesin Complex bind distal enhancer elements in MYC gene promoter _doRelease TRUE _timestamp 2018-02-23 13:08:40 authored [InstanceEdit:9024061] Rothfels, Karen, 2017-09-29 compartment [Compartment:7660] nucleoplasm created [InstanceEdit:9011996] Rothfels, Karen, 2017-07-06 edited [InstanceEdit:9028899] Rothfels, Karen, 2017-11-13 input [EntityWithAccessionedSequence:2127254] MYC gene [nucleoplasm] [Homo sapiens] [Complex:1254381] ESR1 dimer:ESTG [nucleoplasm] [Homo sapiens] [Complex:9011886] FOSB:JUND [nucleoplasm] [Homo sapiens] [Complex:1641505] Cohesin Complex [nucleoplasm] [Homo sapiens] isChimeric FALSE literatureReference [LiteratureReference:9010369] Stimulation of c-myc oncogene expression associated with estrogen-induced proliferation of human breast cancer cells [LiteratureReference:9010372] Transcriptional regulation of c-myc oncogene expression by estrogen in hormone-responsive human breast cancer cells [LiteratureReference:9010364] Mechanism of estrogen activation of c-myc oncogene expression [LiteratureReference:9010377] c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry [LiteratureReference:9010361] Global gene expression analysis of estrogen receptor transcription factor cross talk in breast cancer: identification of estrogen-induced/activator protein-1-dependent genes [LiteratureReference:9010349] Genome-wide analysis of estrogen receptor binding sites [LiteratureReference:9010310] Estrogen induces c-myc gene expression via an upstream enhancer activated by the estrogen receptor and the AP-1 transcription factor [LiteratureReference:9010307] Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators [LiteratureReference:9010286] A CTCF-independent role for cohesin in tissue-specific transcription [LiteratureReference:9010292] Cohesin is required for activation of MYC by estradiol [LiteratureReference:9010298] Cohesin modulates transcription of estrogen-responsive genes [LiteratureReference:9010319] Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation [LiteratureReference:9010345] Gene regulation by cohesin in cancer: is the ring an unexpected party to proliferation? [LiteratureReference:9010290] Cohesin in cancer: chromosome segregation and beyond modified [InstanceEdit:9024084] Rothfels, Karen, 2017-09-29 [InstanceEdit:9028394] Rothfels, Karen, 2017-11-07 [InstanceEdit:9028913] Rothfels, Karen, 2017-11-13 [InstanceEdit:9029193] Rothfels, Karen, 2017-11-14 [InstanceEdit:9038171] Rothfels, Karen, 2018-02-23 [InstanceEdit:9038275] Rothfels, Karen, 2018-02-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name ESR1:ESTG, JUND:FOSB and Cohesin Complex bind distal enhancer elements in MYC gene promoter output [Complex:9011887] MYC gene:ESR1:ESTG:JUND:FOSB:Cohesin Complex [nucleoplasm] [Homo sapiens] precedingEvent
releaseDate 2018-03-21 reviewed [InstanceEdit:9038169] Magnani, Luca, 2018-02-23 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:9011998] R-HSA-9011997.2 summation [Summation:9011841] MYC gene expression is estrogen-responsive and expression of... (hasEvent) [Pathway:9018519] Estrogen-dependent gene expression [Homo sapiens] (precedingEvent) [BlackBoxEvent:9011975] Estrogen-responsive MYC gene expression [Homo sapiens]
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