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Details on Person Estrogen-responsive KDM4B gene expression

Class:Id	BlackBoxEvent:9011966
_displayName	Estrogen-responsive KDM4B gene expression
_doRelease	TRUE
_timestamp	2018-02-23 13:08:59
authored	[InstanceEdit:9024061] Rothfels, Karen, 2017-09-29
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9011967] Rothfels, Karen, 2017-07-06
edited	[InstanceEdit:9028899] Rothfels, Karen, 2017-11-13
input	[EntityWithAccessionedSequence:9011732] KDM4B gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9011656] Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development [LiteratureReference:9011806] KDM4B is a master regulator of the estrogen receptor signalling cascade
modified	[InstanceEdit:9022166] Rothfels, Karen, 2017-09-21 [InstanceEdit:9024098] Rothfels, Karen, 2017-09-29 [InstanceEdit:9028406] Rothfels, Karen, 2017-11-07 [InstanceEdit:9028922] Rothfels, Karen, 2017-11-13 [InstanceEdit:9029205] Rothfels, Karen, 2017-11-14 [InstanceEdit:9038171] Rothfels, Karen, 2018-02-23 [InstanceEdit:9038275] Rothfels, Karen, 2018-02-23 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Estrogen-responsive KDM4B gene expression
output	[EntityWithAccessionedSequence:3214396] KDM4B [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9011949] KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers [Homo sapiens] [Reaction:9011952] ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9011965] Positive gene expression regulation by 'KDM4B gene:nucleoplasm:ESR1:ESTG [nucleoplasm]'
releaseDate	2018-03-21
reviewed	[InstanceEdit:9038169] Magnani, Luca, 2018-02-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9011969] R-HSA-9011966.3
summation	[Summation:9022158] KDM4B regulates its own expression by interacting with the e...
(hasEvent)	[Pathway:9018519] Estrogen-dependent gene expression [Homo sapiens]
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No pathways have been reviewed or authored by Estrogen-responsive KDM4B gene expression (9011966)