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| Class:Id | Summation:9011746 |
|---|---|
| _displayName | Cytokine receptor common subunit gamma (IL2RG) binds Tyrosin... |
| _timestamp | 2017-07-07 09:47:37 |
| created | [InstanceEdit:9011745] Duenas, Corina, 2017-07-06 |
| literatureReference | [LiteratureReference:9010172] Jak3-independent trafficking of the common gamma chain receptor subunit: chaperone function of Jaks revisited [LiteratureReference:451897] Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID |
| modified | [InstanceEdit:9011761] Duenas, Corina, 2017-07-06 [InstanceEdit:9012008] Duenas, Corina, 2017-07-07 |
| text | Cytokine receptor common subunit gamma (IL2RG) binds Tyrosine-protein kinase JAK3(JAK3) (Hofmann et al. 2004). IL2RG is indispensable for JAK3 membrane location, but IL2RG can appear in the cell membrane without JAK3. Moreover an increased IL2RG-JAK3 association is also found after Interleukin-2 stimulation (Rusell et al. 1994). |
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