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Details on Person Robo2 gene expression is stimulated by Hoxa2 and inhibited by Lhx2

Class:Id	BlackBoxEvent:9010527
_displayName	Robo2 gene expression is stimulated by Hoxa2 and inhibited by Lhx2
_doRelease	TRUE
_timestamp	2017-08-04 18:40:51
authored	[InstanceEdit:9009836] Orlic-Milacic, Marija, 2017-06-23
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:9010526] Orlic-Milacic, Marija, 2017-06-27
edited	[InstanceEdit:9014889] Orlic-Milacic, Marija, 2017-08-04
input	[EntityWithAccessionedSequence:9010513] Robo2 gene [nucleoplasm] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9010501] Hox paralog group 2 genes control the migration of mouse pontine neurons through slit-robo signaling [LiteratureReference:9011085] The lhx2 transcription factor controls thalamocortical axonal guidance by specific regulation of robo1 and robo2 receptors
modified	[InstanceEdit:9010536] Orlic-Milacic, Marija, 2017-06-27 [InstanceEdit:9011092] Orlic-Milacic, Marija, 2017-06-29 [InstanceEdit:9014259] Orlic-Milacic, Marija, 2017-07-27 [InstanceEdit:9014891] Orlic-Milacic, Marija, 2017-08-04 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Robo2 gene expression is stimulated by Hoxa2 and inhibited by Lhx2
output	[EntityWithAccessionedSequence:426402] Robo2 [plasma membrane] [Mus musculus]
regulatedBy	[PositiveGeneExpressionRegulation:9010525] Positive gene expression regulation by 'Hoxa2:Robo2 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:9011105] Negative gene expression regulation by 'Lhx2:Robo2 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642467] Negative gene expression regulation by 'Lhx2:Robo2 gene [nucleoplasm]' The lhx2 transcription factor controls thalamocortical axonal guidance by specific regulation of robo1 and robo2 receptors [RegulationReference:9642520] Positive gene expression regulation by 'Hoxa2:Robo2 gene [nucleoplasm]' Hox paralog group 2 genes control the migration of mouse pontine neurons through slit-robo signaling
releaseDate	2017-09-12
reviewed	[InstanceEdit:9014887] Jaworski, Alexander, 2017-07-31
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9010531] R-MMU-9010527.4
summation	[Summation:9010535] In mice, the homeobox transcription factor Hoxa2, which dire...
(inferredFrom)	[BlackBoxEvent:9010523] ROBO2 gene transcription is stimulated by HOXA2 and inhibited by LHX2 [Homo sapiens]
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