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Details on Person Binding of AP1 transcriptional activator complexes to CCND1 promoter

Class:IdReaction:9009371
_displayNameBinding of AP1 transcriptional activator complexes to CCND1 promoter
_doReleaseTRUE
_timestamp2018-02-23 13:08:24
authored[InstanceEdit:9024061] Rothfels, Karen, 2017-09-29
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9009372] Rothfels, Karen, 2017-06-16
edited[InstanceEdit:9028899] Rothfels, Karen, 2017-11-13
input[Complex:9009057] CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] [Homo sapiens]
[Complex:9009373] ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:83836] POU2F1 [nucleoplasm] [Homo sapiens]
[Complex:9009370] ESTG:ESR1 dimer:ATF2:JUN [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:381325] EP300 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9009347] The elements of human cyclin D1 promoter and regulation involved
[LiteratureReference:9009352] Transcriptional regulation of the cyclin D1 gene at a glance
[LiteratureReference:9009325] Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions
[LiteratureReference:9009005] Estrogens and progesterone promote persistent CCND1 gene activation during G1 by inducing transcriptional derepression via c-Jun/c-Fos/estrogen receptor (progesterone receptor) complex assembly to a distal regulatory element and recruitment of cyclin D1 to its own gene promoter
[LiteratureReference:9009340] The AP-1 transcription factor regulates breast cancer cell growth via cyclins and E2F factors
[LiteratureReference:9009368] Estrogen induction of the cyclin D1 promoter: involvement of a cAMP response-like element
[LiteratureReference:9009355] Estrogen regulation of cyclin D1 gene expression in ZR-75 breast cancer cells involves multiple enhancer elements
[LiteratureReference:9008977] A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer
[LiteratureReference:9009039] Pioneer transcription factors: establishing competence for gene expression
[LiteratureReference:9009047] Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions
modified[InstanceEdit:9009657] Rothfels, Karen, 2017-06-21
[InstanceEdit:9024069] Rothfels, Karen, 2017-09-29
[InstanceEdit:9028378] Rothfels, Karen, 2017-11-07
[InstanceEdit:9028900] Rothfels, Karen, 2017-11-13
[InstanceEdit:9029178] Rothfels, Karen, 2017-11-14
[InstanceEdit:9038171] Rothfels, Karen, 2018-02-23
[InstanceEdit:9038275] Rothfels, Karen, 2018-02-23
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameBinding of AP1 transcriptional activator complexes to CCND1 promoter
output[Complex:9009369] CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3:ESTG:ESR1 dimer:JUN:ATF2:POUF21:ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2018-03-21
reviewed[InstanceEdit:9038169] Magnani, Luca, 2018-02-23
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9009377] R-HSA-9009371.2
summation[Summation:9009655] Although there is not a classical estrogen response element ...
(hasEvent)[Pathway:9018519] Estrogen-dependent gene expression [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9009378] Estrogen-responsive CCND1 gene expression [Homo sapiens]
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No pathways have been reviewed or authored by Binding of AP1 transcriptional activator complexes to CCND1 promoter (9009371)