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Details on Person IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction

Class:Id	LiteratureReference:9008564
_displayName	IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
_timestamp	2017-06-12 16:20:15
author	[Person:9008619] Nold-Petry, Claudia A [Person:9008580] Lo, Camden Y [Person:9008605] Rudloff, Ina [Person:9008622] Elgass, Kirstin D [Person:9008594] Li, Suzhao [Person:9008611] Gantier, Michael P [Person:9008598] Lotz-Havla, Amelie S [Person:9008572] Gersting, Søren W [Person:9008610] Cho, Steven X [Person:9008581] Lao, Jason C [Person:9008616] Ellisdon, Andrew M [Person:9008589] Rotter, Björn [Person:8848523] Azam, Tania [Person:9008617] Mangan, Niamh E [Person:9008595] Rossello, Fernando J [Person:8938126] Whisstock, James C [Person:8848522] Bufler, Philip [Person:5690304] Garlanda, Cecilia [Person:1222267] Mantovani, A [Person:5690312] Dinarello, Charles A [Person:9008573] Nold, Marcel F
created	[InstanceEdit:9008601] Varusai, Thawfeek, 2017-06-12
journal	Nat. Immunol.
pages	354-65
pubMedIdentifier	25729923
title	IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
volume	16
year	2015
(literatureReference)	[Summation:198766] Activation of TRKA by NGF triggers STAT3 phosphorylation at ... [Summation:9008592] Interleukins (IL) are immunomodulatory proteins that elicit ... [Summation:9008609] Interleukins (IL) are immunomodulatory proteins that elicit ... [Summation:9008690] Serine/threonine protein kinase TBK1 plays a key role in reg... [Summation:9009073] Signal transducer and activator of transcription 3 (STAT3) a... [Reaction:198732] STAT3 activation [Homo sapiens] [Reaction:9008577] IL37:IL18R1 binds SIGIRR [Homo sapiens] [BlackBoxEvent:9009072] STAT3 phosphorylation [Homo sapiens] [RegulationReference:9642223] Positive regulation by 'IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane]' IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
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No pathways have been reviewed or authored by IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction (9008564)