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Details on Person Mouse Dlx5, activated in response to Bmp2 signaling, binds t...

Class:IdSummation:9007733
_displayNameMouse Dlx5, activated in response to Bmp2 signaling, binds t...
_timestamp2017-06-05 15:20:53
created[InstanceEdit:9007734] Orlic-Milacic, Marija, 2017-06-02
literatureReference[LiteratureReference:9007804] Dlx5 drives Runx2 expression and osteogenic differentiation in developing cranial suture mesenchyme
[LiteratureReference:9007794] Downregulation of Dlx5 and Dlx6 expression by Hand2 is essential for initiation of tongue morphogenesis
[LiteratureReference:9007714] Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter
[LiteratureReference:9007782] The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development
modified[InstanceEdit:9007808] Orlic-Milacic, Marija, 2017-06-05
textMouse Dlx5, activated in response to Bmp2 signaling, binds three sites in the mouse Runx2 gene promoter (Lee et al. 2005). Based on several studies, Dlx6 is suggested to be redundant with Dlx5 in the regulation of Runx2 expression (Robledo et al. 2002, Holleville et al. 2007, Barron et al. 2011) and is therefore shown as a candidate transcriptional regulator of Runx2.
(summation)[Reaction:9007731] Dlx5,(Dlx6) binds Runx2 gene promoter [Mus musculus]
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