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Details on Person Dlx5,(Dlx6) binds Runx2 gene promoter

Class:Id	Reaction:9007731
_displayName	Dlx5,(Dlx6) binds Runx2 gene promoter
_doRelease	TRUE
_timestamp	2017-08-14 17:55:02
authored	[InstanceEdit:9007734] Orlic-Milacic, Marija, 2017-06-02
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9007734] Orlic-Milacic, Marija, 2017-06-02
edited	[InstanceEdit:9015332] Orlic-Milacic, Marija, 2017-08-09
input	[EntityWithAccessionedSequence:8985318] Runx2 gene [nucleoplasm] [Mus musculus] [CandidateSet:9007791] Dlx5,(Dlx6) [nucleoplasm] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9007714] Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter [LiteratureReference:9007782] The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development
modified	[InstanceEdit:9007793] Orlic-Milacic, Marija, 2017-06-05 [InstanceEdit:9007808] Orlic-Milacic, Marija, 2017-06-05 [InstanceEdit:9007810] Orlic-Milacic, Marija, 2017-06-05 [InstanceEdit:9014261] Orlic-Milacic, Marija, 2017-07-27 [InstanceEdit:9015322] Orlic-Milacic, Marija, 2017-08-09 [InstanceEdit:9015339] Orlic-Milacic, Marija, 2017-08-10 [InstanceEdit:9016598] Orlic-Milacic, Marija, 2017-08-14 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Dlx5,(Dlx6) binds Runx2 gene promoter
output	[Complex:9007730] Dlx5,(Dlx6):Runx2 gene [nucleoplasm] [Mus musculus]
regulatedBy	[PositiveRegulation:9007739] Positive regulation by 'Bmp2 dimer [extracellular region]'
regulationReference	[RegulationReference:9641346] Positive regulation by 'Bmp2 dimer [extracellular region]' Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter
releaseDate	2017-09-12
reviewed	[InstanceEdit:9015314] Ducy, Patricia, 2017-08-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9007735] R-MMU-9007731.4
summation	[Summation:9007733] Mouse Dlx5, activated in response to Bmp2 signaling, binds t...
(inferredFrom)	[Reaction:9007707] DLX5,(DLX6) binds RUNX2 gene promoter [Homo sapiens]
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No pathways have been reviewed or authored by Dlx5,(Dlx6) binds Runx2 gene promoter (9007731)