Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person CHEK1 phosphorylates E2F6

Class:IdReaction:9007539
_displayNameCHEK1 phosphorylates E2F6
_doReleaseTRUE
_timestamp2017-07-27 12:55:33
authored[InstanceEdit:9007684] Orlic-Milacic, Marija, 2017-05-31
catalystActivity[CatalystActivity:182636] protein serine/threonine kinase activity of p-S317,S345-CHEK1 [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9007538] Orlic-Milacic, Marija, 2017-05-31
edited[InstanceEdit:9007684] Orlic-Milacic, Marija, 2017-05-31
input[EntityWithAccessionedSequence:8953089] E2F6 [nucleoplasm] [Homo sapiens]
[SimpleEntity:29358] ATP [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:9007091] Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription
modified[InstanceEdit:9014244] Orlic-Milacic, Marija, 2017-07-27
[InstanceEdit:9014245] Orlic-Milacic, Marija, 2017-07-27
[InstanceEdit:9014246] Orlic-Milacic, Marija, 2017-07-27
[InstanceEdit:9014256] Orlic-Milacic, Marija, 2017-07-27
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCHEK1 phosphorylates E2F6
output[EntityWithAccessionedSequence:9007536] p-S12-E2F6 [nucleoplasm] [Homo sapiens]
[SimpleEntity:113582] ADP [nucleoplasm]
releaseDate2017-09-12
reviewed[InstanceEdit:9005633] Herlihy, Anna, 2017-05-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9007540] R-HSA-9007539.2
summation[Summation:9007535] CHEK1 (Chk1), activated by ATR in response to replication st...
(hasEvent)[Pathway:8953750] Transcriptional Regulation by E2F6 [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by CHEK1 phosphorylates E2F6 (9007539)