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Details on Person Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription

Class:IdLiteratureReference:9007091
_displayNameChk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription
_timestamp2017-05-26 14:40:11
author[Person:9007095] Bertoli, Cosetta
[Person:9007088] Klier, Steffi
[Person:9007092] McGowan, Clare
[Person:9007089] Wittenberg, Curt
[Person:9007096] de Bruin, Robertus A M
created[InstanceEdit:9007097] Orlic-Milacic, Marija, 2017-05-26
journalCurr. Biol.
pages1629-37
pubMedIdentifier23954429
titleChk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription
volume23
year2013
(literatureReference)[RegulationReference:9641239] Negative regulation by 'p-S317,S345-CHEK1 [nucleoplasm]' Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription
[RegulationReference:9641521] Negative regulation by 'E2F6:(TFDP1,TFDP2):RRM2 gene [nucleoplasm]' Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription
[RegulationReference:9641986] Negative regulation by 'p-S317,S345-CHEK1 [nucleoplasm]' Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription
[RegulationReference:9642014] Negative gene expression regulation by 'E2F6:(TFDP1,TFDP2):RAD51 gene [nucleoplasm]' Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription
[Complex:9007547] E2F6:(TFDP1,TFDP2):RAD51 gene [nucleoplasm] [Homo sapiens]
[Complex:9007590] E2F6:(TFDP1,TFDP2):RRM2 gene [nucleoplasm] [Homo sapiens]
[Pathway:8953750] Transcriptional Regulation by E2F6 [Homo sapiens]
[BlackBoxEvent:8961982] RRM2 gene expression is stimulated by E2F1 and inhibited by E2F6 [Homo sapiens]
[Reaction:9007539] CHEK1 phosphorylates E2F6 [Homo sapiens]
[Reaction:9007546] E2F6 binds RAD51 gene promoter [Homo sapiens]
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No pathways have been reviewed or authored by Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription (9007091)