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Details on Person Stat4 is phosphorylated by p-Jak2 and/or p-Y-Tyk2 after Il12:Il12r interaction

Class:Id	BlackBoxEvent:9006466
_displayName	Stat4 is phosphorylated by p-Jak2 and/or p-Y-Tyk2 after Il12:Il12r interaction
_doRelease	TRUE
_timestamp	2017-05-17 13:40:59
authored	[InstanceEdit:8950107] Duenas, Corina, 2016-12-02
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9006469] Duenas, Corina, 2017-05-16
edited	[InstanceEdit:9006617] Jupe, Steve, 2017-05-17
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [Complex:9006461] 2xStat4:Il12a:Il12b:Il12rb1:p-Y800-Il12rb2:p-Y-Tyk2:p-Jak2 [plasma membrane] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:8950738] Identification of a STAT4 binding site in the interleukin-12 receptor required for signaling
modified	[InstanceEdit:9006625] Jupe, Steve, 2017-05-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Stat4 is phosphorylated by p-Jak2 and/or p-Y-Tyk2 after Il12:Il12r interaction
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [Complex:9006474] 2xp-Y693-Stat4:Il12a:Il12b:Il12rb1:p-Y800-Il12rb2:p-Y-Tyk2:p-Jak2 [plasma membrane] [Mus musculus]
releaseDate	2017-06-12
reviewed	[InstanceEdit:9006071] van de Vosse, Esther, 2017-05-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9006481] R-MMU-9006466.2
summation	[Summation:9006471] Signal transducer and activator of transcription 4 (STAT4) i...
(inferredFrom)	[BlackBoxEvent:8950354] STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interaction [Homo sapiens]
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