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Query author contributions in Reactome

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Details on Person Phosphorylated Signal transducer and activator of transcript...

Class:IdSummation:9005431
_displayNamePhosphorylated Signal transducer and activator of transcript...
_timestamp2024-02-26 21:18:16
created[InstanceEdit:9005452] Duenas, Corina, 2017-05-09
literatureReference[LiteratureReference:8987116] Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2
[LiteratureReference:9009139] The cationic cytokine IL-26 differentially modulates virus infection in culture
[LiteratureReference:9009241] Transcription Factor STAT3 as a Novel Molecular Target for Cancer Prevention
[LiteratureReference:6784788] Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3
modified[InstanceEdit:9009145] Duenas, Corina, 2017-06-15
[InstanceEdit:9009247] Duenas, Corina, 2017-06-16
[InstanceEdit:9009474] Duenas, Corina, 2017-06-19
[InstanceEdit:9010848] Duenas, Corina, 2017-06-28
[InstanceEdit:9010942] Duenas, Corina, 2017-06-28
[InstanceEdit:9011370] Jupe, Steve, 2017-06-30
[InstanceEdit:9011694] Duenas, Corina, 2017-07-04
[InstanceEdit:9863024] Matthews, Lisa, 2024-02-26
textPhosphorylated Signal transducer and activator of transcription 3 (STAT3) and Signal transducer and activator of transcription 1 alpha/beta (STAT1) are believed to dissociate from the Interleukin-26 (IL26) receptor complex. This is a black-box event because dissociation is inferred from other interleukin signaling cascades, e.g. Interleukin-10 (Niemand et al. 2003, Braum et al. 2013, Xiong et al. 2014, Sheikh et al. 2006) where dissociation occurs before dimerization and translocation to the nucleus.
(summation)[BlackBoxEvent:8987230] p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 [Homo sapiens]
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