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Details on Person Interferon regulatory factor 7 (IRF7) binds to the phosphory...
| Class:Id | Summation:9005386 |
|---|---|
| _displayName | Interferon regulatory factor 7 (IRF7) binds to the phosphory... |
| _timestamp | 2017-05-19 10:39:45 |
| created | [InstanceEdit:9005452] Duenas, Corina, 2017-05-09 |
| literatureReference | [LiteratureReference:8987205] Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases |
| modified | [InstanceEdit:9005499] Duenas, Corina, 2017-05-09 [InstanceEdit:9006768] Duenas, Corina, 2017-05-19 |
| text | Interferon regulatory factor 7 (IRF7) binds to the phosphorylated STAT1:STAT2 dimer (Signal transducer and activator of transcription 1-alpha/beta and Signal transducer and activator of transcription 2) after Interferon lambda-1 (IFNL1 or IL29) stimulus. After IFNL1 (and Interferon alpha-2 (IFNA2)) stimulation there is a induction of STAT1 and IRF7, whereas no significant induction of IRF3, IRF9, or STAT3 is observed for either of the cytokines (Zhou et al. 2007). This is a black box event because there is not evidence about the binding region between this IRF7 and the dimer after the stimulation. |
| (summation) | [BlackBoxEvent:8987251] IRF7 binds to p-Y-STAT1:p-Y-STAT2 after IFNL1 stimulus [Homo sapiens] |
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No pathways have been reviewed or authored by Interferon regulatory factor 7 (IRF7) binds to the phosphory... (9005386)
