Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person IL10RB binds TYK2

Class:IdReaction:8987223
_displayNameIL10RB binds TYK2
_doReleaseTRUE
_timestamp2017-12-04 16:46:10
authored[InstanceEdit:8982160] Duenas, Corina, 2017-03-16
compartment[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:8987035] Duenas, Corina, 2017-05-05
edited[InstanceEdit:9028437] Jupe, Steve, 2017-11-07
input[EntityWithAccessionedSequence:448423] IL10RB [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:877348] TYK2 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8987085] The molecular basis of IL-10 function: from receptor structure to the onset of signaling
[LiteratureReference:8987116] Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2
modified[InstanceEdit:9005492] Duenas, Corina, 2017-05-09
[InstanceEdit:9006768] Duenas, Corina, 2017-05-19
[InstanceEdit:9015130] Duenas, Corina, 2017-08-08
[InstanceEdit:9016466] Duenas, Corina, 2017-08-14
[InstanceEdit:9028447] Jupe, Steve, 2017-11-07
[InstanceEdit:9029253] Jupe, Steve, 2017-11-15
[InstanceEdit:9031943] Rothfels, Karen, 2017-12-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameIL10RB binds TYK2
output[Complex:6784360] IL10RB:TYK2 [plasma membrane] [Homo sapiens]
releaseDate2017-12-13
reviewed[InstanceEdit:9029252] Datta, Sandip K, 2017-11-15
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8987340] R-HSA-8987223.3
summation[Summation:8987081] Interleukin-10 receptor subunit beta (IL10RB, IL10R2) binds ...
(hasEvent)[Pathway:8854691] Interleukin-20 family signaling [Homo sapiens]
(precedingEvent)[Reaction:448661] IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 [Homo sapiens]
[Reaction:8854645] IL22:IL22RA1:JAK1 binds IL10RB:TYK2 [Homo sapiens]
[Reaction:8986480] IL26:IL20RA:JAK1 binds IL10RB:TYK2 [Homo sapiens]
[BlackBoxEvent:8987105] IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by IL10RB binds TYK2 (8987223)