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Details on Person IL24:IL22RA1:p-JAK1:IL20RB binds STAT3

Class:Id	BlackBoxEvent:8987063
_displayName	IL24:IL22RA1:p-JAK1:IL20RB binds STAT3
_doRelease	TRUE
_timestamp	2017-11-15 09:06:58
authored	[InstanceEdit:8982160] Duenas, Corina, 2017-03-16
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:8987035] Duenas, Corina, 2017-05-05
edited	[InstanceEdit:9028437] Jupe, Steve, 2017-11-07
input	[Complex:8986999] IL24:IL22RA1:p-JAK1:IL20RB [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:539044] STAT3 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:448739] Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions [LiteratureReference:8987142] Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 [LiteratureReference:9005345] Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhanced in inflammatory bowel disease
modified	[InstanceEdit:9005492] Duenas, Corina, 2017-05-09 [InstanceEdit:9006768] Duenas, Corina, 2017-05-19 [InstanceEdit:9009145] Duenas, Corina, 2017-06-15 [InstanceEdit:9009230] Duenas, Corina, 2017-06-16 [InstanceEdit:9011702] Duenas, Corina, 2017-07-04 [InstanceEdit:9015130] Duenas, Corina, 2017-08-08 [InstanceEdit:9016466] Duenas, Corina, 2017-08-14 [InstanceEdit:9028447] Jupe, Steve, 2017-11-07 [InstanceEdit:9029253] Jupe, Steve, 2017-11-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	STAT3 binds to IL24:IL22RA1:p-JAK1:IL20RB STAT3 binds to IL24:IL22RA1:p-JAK1:IL20RB STAT3 binds to IL24:IL22RA1:p-JAK1:IL20RB
output	[Complex:8987189] IL24:IL22RA1:p-JAK1:IL20RB:STAT3 [plasma membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:8987012] IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 [Homo sapiens] [BlackBoxEvent:448708] IL24 binds to IL22RA1:JAK1:IL20RB [Homo sapiens]
releaseDate	2017-12-13
reviewed	[InstanceEdit:9029252] Datta, Sandip K, 2017-11-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8987368] R-HSA-8987063.2
summation	[Summation:9005442] Signal transducer and activator of transcription 3 (STAT3) i...
(hasEvent)	[Pathway:8854691] Interleukin-20 family signaling [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:8987096] IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 [Homo sapiens]
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No pathways have been reviewed or authored by IL24:IL22RA1:p-JAK1:IL20RB binds STAT3 (8987063)