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Details on Person Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR

Class:IdLiteratureReference:8986952
_displayNameActivity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR
_timestamp2017-05-05 14:15:07
author[Person:8986968] Ebert, Daniel H
[Person:8986961] Gabel, Harrison W
[Person:8986969] Robinson, Nathaniel D
[Person:8986966] Kastan, Nathaniel R
[Person:8986960] Hu, Linda S
[Person:8986958] Cohen, Sonia
[Person:8986954] Navarro, Adrija J
[Person:4090391] Lyst, Matthew J
[Person:8986965] Ekiert, Robert
[Person:3730691] Bird, Adrian P
[Person:3928198] Greenberg, Michael E
created[InstanceEdit:8986967] Orlic-Milacic, Marija, 2017-05-05
journalNature
pages341-5
pubMedIdentifier23770587
titleActivity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR
volume499
year2013
(literatureReference)[Complex:9005564] MECP2:NCoR/SMRT complex [nucleoplasm] [Homo sapiens]
[CandidateSet:9005569] MECP2 mutants R306C,(R306H) [nucleoplasm] [Homo sapiens]
[DefinedSet:9005587] Active PRKACA,CaMK IV [nucleoplasm] [Homo sapiens]
[RegulationReference:9641774] Negative regulation by 'Active PRKACA,CaMK IV [nucleoplasm]' Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR
[CatalystActivityReference:9643443] calcium-dependent protein kinase activity of Active PRKACA,CaMK IV [nucleoplasm] Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR
[Summation:8986941] MECP2 binds the nuclear receptor co-repressor complex (NCoR/...
[Reaction:8986937] MECP2 is phosphorylated at T308 [Homo sapiens]
[Reaction:8986939] MECP2 binds the NCoR/SMRT complex [Homo sapiens]
[Pathway:8986944] Transcriptional Regulation by MECP2 [Homo sapiens]
[FailedReaction:9005561] Active PKA, CaMK IV do not phosphorylate MECP2 mutants R306C,(R306H) at T308 [Homo sapiens]
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