Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person PRSS3 hydrolyzes SPINK1

Class:IdReaction:8986420
_displayNamePRSS3 hydrolyzes SPINK1
_doReleaseFALSE
_timestamp2017-04-26 22:06:25
catalystActivity[CatalystActivity:8986426] serine-type endopeptidase activity of PRSS3 [extracellular region]
catalystActivityReference[CatalystActivityReference:9643526] serine-type endopeptidase activity of PRSS3 [extracellular region] Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors
compartment[Compartment:984] extracellular region
created[InstanceEdit:8986422] D'Eustachio, Peter, 2017-04-26
goBiologicalProcess[GO_BiologicalProcess:2133561] positive regulation of serine-type endopeptidase activity
input[EntityWithAccessionedSequence:8986413] SPINK1 [extracellular region] [Homo sapiens]
[SimpleEntity:109276] H2O [extracellular region]
[SimpleEntity:109276] H2O [extracellular region]
[SimpleEntity:109276] H2O [extracellular region]
[SimpleEntity:109276] H2O [extracellular region]
isChimericFALSE
literatureReference[LiteratureReference:8985860] Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors
modified[InstanceEdit:8986441] D'Eustachio, Peter, 2017-04-26
[InstanceEdit:9643047] Wu, G, 2019-04-04
namePRSS3 hydrolyzes SPINK1
output[EntityWithAccessionedSequence:8986424] SPINK1(24-28) [extracellular region] [Homo sapiens]
[EntityWithAccessionedSequence:8986409] SPINK1(29-41) [extracellular region] [Homo sapiens]
[EntityWithAccessionedSequence:8986414] SPINK1(42-67) [extracellular region] [Homo sapiens]
[EntityWithAccessionedSequence:8986423] SPINK1(68-75) [extracellular region] [Homo sapiens]
[EntityWithAccessionedSequence:8986410] SPINK1(76-79) [extracellular region] [Homo sapiens]
precedingEvent
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8986432] R-HSA-8986420.1
(hasEvent)[Pathway:8985741] Trypsin, chymotrypsin, and carboxypeptidase activation and action on dietary protein [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by PRSS3 hydrolyzes SPINK1 (8986420)