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Details on Person IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B

Class:Id	Reaction:8985929
_displayName	IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B
_doRelease	TRUE
_timestamp	2022-12-29 15:53:58
authored	[InstanceEdit:8985906] Duenas, Corina, 2017-04-21
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:8985906] Duenas, Corina, 2017-04-21
edited	[InstanceEdit:9607062] Jassal, Bijay, 2018-04-27
input	[Complex:8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] [Homo sapiens] [DefinedSet:1433551] STATs [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8985894] A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9 [LiteratureReference:8985999] Heteromerization of the gammac chain with the interleukin-9 receptor alpha subunit leads to STAT activation and prevention of apoptosis
modified	[InstanceEdit:9010180] Duenas, Corina, 2017-06-26 [InstanceEdit:9011754] Duenas, Corina, 2017-07-06 [InstanceEdit:9015726] Duenas, Corina, 2017-08-11 [InstanceEdit:9023006] Duenas, Corina, 2017-09-26 [InstanceEdit:9027580] Jupe, Steve, 2017-11-03 [InstanceEdit:9606932] Jassal, Bijay, 2018-04-27 [InstanceEdit:9607065] Jassal, Bijay, 2018-04-30 [InstanceEdit:9607349] Jassal, Bijay, 2018-05-04 [InstanceEdit:9634149] Jassal, Bijay, 2019-01-07 [InstanceEdit:9822872] D'Eustachio, Peter, 2022-12-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B STAT1, STAT3 or STAT5 bind IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3
output	[Complex:8985893] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:8985973] IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 [Homo sapiens] [BlackBoxEvent:8985914] IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 [Homo sapiens]
releaseDate	2018-06-12
reviewed	[InstanceEdit:8854753] Meldal, Birgit, 2016-01-28 [InstanceEdit:9607063] Limon, Paula, 2018-04-27
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8986008] R-HSA-8985929.4
summation	[Summation:8985909] Signal transducer and activator of transcription 1-alpha/bet...
(hasEvent)	[Pathway:8985947] Interleukin-9 signaling [Homo sapiens]
(precedingEvent)	[Reaction:8985988] IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9778551] Update Tracker - [Reaction:8985929] IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B - v68:[add_removeInput] [_UpdateTracker:9846679] Update Tracker - [Reaction:8985929] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B - v84:[modifyText]
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No pathways have been reviewed or authored by IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (8985929)