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Details on Person p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3

Class:Id	BlackBoxEvent:8985900
_displayName	p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3
_doRelease	TRUE
_timestamp	2022-12-29 15:54:14
authored	[InstanceEdit:8985906] Duenas, Corina, 2017-04-21
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8985906] Duenas, Corina, 2017-04-21
edited	[InstanceEdit:9607062] Jassal, Bijay, 2018-04-27
input	[Complex:8985982] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8985894] A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9 [LiteratureReference:8985967] IL-9 induces CCL11 expression via STAT3 signalling in human airway smooth muscle cells [LiteratureReference:9010453] STAT5 activation is required for interleukin-9-dependent growth and transformation of lymphoid cells [LiteratureReference:9010464] Interleukin-9 (IL-9) induces cell growth arrest associated with sustained signal transducer and activator of transcription activation in lymphoma cells overexpressing the IL-9 receptor
modified	[InstanceEdit:9010180] Duenas, Corina, 2017-06-26 [InstanceEdit:9023006] Duenas, Corina, 2017-09-26 [InstanceEdit:9027585] Jupe, Steve, 2017-11-03 [InstanceEdit:9606932] Jassal, Bijay, 2018-04-27 [InstanceEdit:9607065] Jassal, Bijay, 2018-04-30 [InstanceEdit:9607349] Jassal, Bijay, 2018-05-04 [InstanceEdit:9822872] D'Eustachio, Peter, 2022-12-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 dissociates from p-Y-STAT1, p-Y705-STAT3, p-STAT5
output	[Complex:8985997] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] [Homo sapiens] [DefinedSet:9010175] p-Y701-STAT1,p-Y705-STAT3,p-Y694-STAT5A,p-STAT5B [cytosol] [Homo sapiens]
precedingEvent	[Reaction:8985988] IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 [Homo sapiens] [Reaction:8985929] IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B [Homo sapiens]
releaseDate	2018-06-12
reviewed	[InstanceEdit:8854753] Meldal, Birgit, 2016-01-28 [InstanceEdit:9607063] Limon, Paula, 2018-04-27
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8986037] R-HSA-8985900.3
summation	[Summation:8985979] Signal transducer and activator of transcription 1-alpha/bet...
(hasEvent)	[Pathway:8985947] Interleukin-9 signaling [Homo sapiens]
(precedingEvent)	[Reaction:8985943] p-Y701-STAT1 dimerizes [Homo sapiens] [BlackBoxEvent:8985950] p-Y694-STAT5A, p-STAT5B dimerizes [Homo sapiens] [Reaction:8985966] p-Y701-STAT1 binds p-Y705-STAT3 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9846788] Update Tracker - [BlackBoxEvent:8985900] p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 - v84:[modifyText]
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No pathways have been reviewed or authored by p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 (8985900)