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Details on Person BDMD1 activates TMPRSS15

Class:Id	Reaction:8985750
_displayName	BDMD1 activates TMPRSS15
_doRelease	FALSE
_timestamp	2017-04-20 17:32:00
catalystActivity	[CatalystActivity:8985767] serine-type endopeptidase activity of BDMD1 [extracellular region]
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8985753] D'Eustachio, Peter, 2017-04-20
goBiologicalProcess	[GO_BiologicalProcess:172710] zymogen activation
inferredFrom	[Reaction:8985755] BDMD1 activates TMPRSS15 [Bos taurus]
input	[EntityWithAccessionedSequence:8985742] TMPRSS15 [plasma membrane] [Homo sapiens] [SimpleEntity:109276] H2O [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:8985757] Membrane-anchored serine proteases in health and disease [LiteratureReference:8985746] Histochemical demonstration of enteropeptidase activity. New method with a synthetic substrate and its comparison with the trypsinogen procedure [LiteratureReference:8985749] Activation of recombinant proenteropeptidase by duodenase [LiteratureReference:8985766] Expression of duodenase-like protein in epitheliocytes of Brunner's glands in human duodenal mucosa [LiteratureReference:8985737] Immunofluorescent localisation of enterokinase in human small intestine
modified	[InstanceEdit:8985789] D'Eustachio, Peter, 2017-04-20
name	BDMD1 activates TMPRSS15
output	[Complex:8985738] TMPRSS15 complex [plasma membrane] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8985770] R-HSA-8985750.1
summation	[Summation:8985760] This reaction is inferred from the properties of bovine duod...
(hasEvent)	[Pathway:8985741] Trypsin, chymotrypsin, and carboxypeptidase activation and action on dietary protein [Homo sapiens]
(precedingEvent)	[Reaction:8985787] Enteropeptidase TMPRSS15 activates trypsin-1 (PRSS1) [Homo sapiens] [Reaction:8985861] Enteropeptidase TMPRSS15 activates trypsin-3 (PRSS3) [Homo sapiens] [Reaction:8985864] Enteropeptidase TMPRSS15 activates trypsin-2 (PRSS2) [Homo sapiens]
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No pathways have been reviewed or authored by BDMD1 activates TMPRSS15 (8985750)