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Details on Person Extracellular PRSS2 (trypsin-2; anionic trypsin) catalyzes t...
| Class:Id | Summation:8985679 |
|---|---|
| _displayName | Extracellular PRSS2 (trypsin-2; anionic trypsin) catalyzes t... |
| _timestamp | 2017-04-18 19:34:01 |
| created | [InstanceEdit:8985668] D'Eustachio, Peter, 2017-04-18 |
| modified | [InstanceEdit:8985680] D'Eustachio, Peter, 2017-04-18 |
| text | Extracellular PRSS2 (trypsin-2; anionic trypsin) catalyzes the cleavage of the propeptide of proCELA3B, releasing the mature active form of the enzyme. In the body this reaction takes place in the lumen of the small intestine. Anionic trypsin (PRSSS2) catalyzes activation of the homologous enzyme CELA2A more efficiently that cationic trypsin (PRSS1) in assays with purified proteins vitro so PRSS2 is inferred to act preferentially on CELA3B as well (Shen et al. 1987; Szepessy & Sahin-Toth 2006). |
| (summation) | [Reaction:8985535] PRSS2 activates proCELA3B [Homo sapiens] |
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No pathways have been reviewed or authored by Extracellular PRSS2 (trypsin-2; anionic trypsin) catalyzes t... (8985679)
