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Details on Person Extracellular PRSS2 (trypsin-2; anionic trypsin) catalyzes t...
| Class:Id | Summation:8985666 |
|---|---|
| _displayName | Extracellular PRSS2 (trypsin-2; anionic trypsin) catalyzes t... |
| _timestamp | 2017-04-18 19:34:01 |
| created | [InstanceEdit:8985668] D'Eustachio, Peter, 2017-04-18 |
| modified | [InstanceEdit:8985680] D'Eustachio, Peter, 2017-04-18 |
| text | Extracellular PRSS2 (trypsin-2; anionic trypsin) catalyzes the cleavage of the propeptide of proCELA2B, releasing the mature active form of the enzyme. In the body this reaction takes place in the lumen of the small intestine. While both anionic (PRSS2) and cationic (PRSS1) forms of trypsin can catalyze this reaction, the anionic form is substantially more active in assays in vitro with purified proteins, so PRSS2 is annotated as the catalyst here (Shirasu et al. 1987; Szepessy & Sahin-Toth 2006). |
| (summation) | [Reaction:8985514] PRSS2 activates proCELA2B [Homo sapiens] |
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No pathways have been reviewed or authored by Extracellular PRSS2 (trypsin-2; anionic trypsin) catalyzes t... (8985666)
