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Query author contributions in Reactome

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Details on Person Autoactivation of proPGC

Class:IdReaction:8985178
_displayNameAutoactivation of proPGC
_doReleaseFALSE
_timestamp2017-04-11 21:06:16
catalystActivity[CatalystActivity:8984755] aspartic-type endopeptidase activity of proPGC [extracellular region]
catalystActivityReference[CatalystActivityReference:9643291] aspartic-type endopeptidase activity of proPGC [extracellular region] A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins
compartment[Compartment:984] extracellular region
created[InstanceEdit:8985184] D'Eustachio, Peter, 2017-04-11
goBiologicalProcess[GO_BiologicalProcess:172710] zymogen activation
input[EntityWithAccessionedSequence:8984742] proPGC [extracellular region] [Homo sapiens]
[SimpleEntity:109276] H2O [extracellular region]
isChimericFALSE
literatureReference[LiteratureReference:5685896] A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins
[LiteratureReference:8984747] Human progastricsin. Analysis of intermediates during activation into gastricsin and determination of the amino acid sequence of the propart
modified[InstanceEdit:8985194] D'Eustachio, Peter, 2017-04-11
[InstanceEdit:9643047] Wu, G, 2019-04-04
nameAutoactivation of proPGC
output[EntityWithAccessionedSequence:8984769] PGC [extracellular region] [Homo sapiens]
[EntityWithAccessionedSequence:8984751] PGC propeptide [extracellular region] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8985192] R-HSA-8985178.1
summation[Summation:8985187] proPGC (gastricsin precursor, also known as pepsinogen-C) ca...
(hasEvent)[Pathway:8984749] Pepsin activation and action on dietary protein [Homo sapiens]
(precedingEvent)[Reaction:8985177] PGC hydrolyzes dietary proteins [Homo sapiens]
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No pathways have been reviewed or authored by Autoactivation of proPGC (8985178)
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