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Details on Person Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3

Class:IdLiteratureReference:8985106
_displayNameStructural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3
_timestamp2017-04-11 20:40:57
author[Person:5359270] Donovan, Jesse
[Person:8985089] Whitney, Gena
[Person:8985141] Rath, Sneha
[Person:8983639] Korennykh, Alexei
created[InstanceEdit:8985092] Shamovsky, Veronica, 2017-04-11
journalProc. Natl. Acad. Sci. U.S.A.
pages3949-54
pubMedIdentifier25775560
titleStructural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3
volume112
year2015
(literatureReference)[Summation:8983638] 2′-5′-Oligoadenylate synthetase 3 (OAS3) is a template-indep...
[Summation:8985142] Oligoadenylate synthetase 3 (OAS3) is an interferon-inducibl...
[Summation:9987128] During infection with positive-sense RNA viruses such as fla...
[Summation:9987138] Oligoadenylate synthetase 3 (OAS3) is an interferon-inducibl...
[Reaction:8985157] OAS3 binds viral dsRNA intermediates produced by (+)ssRNA virus [Homo sapiens]
[Reaction:9985962] OAS3 binds IAV dsRNA intermediate [Homo sapiens]
[CatalystActivityReference:9986167] 2'-5'-oligoadenylate synthetase activity of OAS3:viral dsRNA intermediates [cytosol] Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3
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