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Details on Person dsRNA intermediate produced by (+)ssRNA virus [cytosol]

Class:Id	DefinedSet:8985076
_displayName	dsRNA intermediate produced by (+)ssRNA virus [cytosol]
_timestamp	2026-03-26 20:59:28
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8985092] Shamovsky, Veronica, 2017-04-11
disease	[Disease:3134794] viral infectious disease
goCellularComponent	[Compartment:436407] host cell cytosol
hasMember	[EntityWithAccessionedSequence:9985886] WNV (-)ssRNA genome replicate with secondary dsRNA structure [cytosol] [West Nile virus] [EntityWithAccessionedSequence:9922964] DENV -ssRNA genome replicate with secondary dsRNA structure [cytosol] [Dengue virus type 2] [EntityWithAccessionedSequence:9691533] SIV stem-loop m7G(5')pppA-genomic RNA [cytosol] [Sindbis virus]
literatureReference	[LiteratureReference:8985043] Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses [LiteratureReference:8983670] Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection [LiteratureReference:9985968] The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway
modified	[InstanceEdit:9031715] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9037720] Shamovsky, Veronica, 2018-02-20 [InstanceEdit:9840737] Shamovsky, Veronica, 2023-07-25 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9986180] Shamovsky, Veronica, 2026-03-26 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15
name	dsRNA intermediate produced by (+)ssRNA virus OAS3 ligand
species	[Species:8985057] Sindbis virus [Species:8983656] West Nile virus [Species:3244621] Dengue virus type 2
stableIdentifier	[StableIdentifier:8985168] R-NUL-8985076.10
(hasComponent)	[Complex:8985156] OAS3:viral dsRNA intermediates [cytosol] [Homo sapiens]
(input)	[Reaction:8985157] OAS3 binds viral dsRNA intermediates produced by (+)ssRNA virus [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9906106] Update Tracker - [DefinedSet:8985076] OAS3 ligand [cytosol] - v86:[addDisease]
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No pathways have been reviewed or authored by dsRNA intermediate produced by (+)ssRNA virus [cytosol] (8985076)