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Details on Person Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1

Class:Id	BlackBoxEvent:8983294
_displayName	Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1
_doRelease	TRUE
_timestamp	2017-08-22 21:35:20
authored	[InstanceEdit:9014998] Duenas, Corina, 2017-08-07
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8983295] Duenas, Corina, 2017-03-23
edited	[InstanceEdit:9015192] Duenas, Corina, 2017-08-09
input	[Complex:8983169] Il15:Il15ra:p-Y-Il2rb:p-Y-Il2rg:p-Y-Jak1:p-Y-Jak3:Shc1 [plasma membrane] [Mus musculus] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:8983265] The docking molecule gab2 is induced by lymphocyte activation and is involved in signaling by interleukin-2 and interleukin-15 but not other common gamma chain-using cytokines [LiteratureReference:507926] New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway
modified	[InstanceEdit:8983903] Duenas, Corina, 2017-03-31 [InstanceEdit:9007328] Duenas, Corina, 2017-05-30 [InstanceEdit:9009893] Duenas, Corina, 2017-06-23 [InstanceEdit:9011615] Duenas, Corina, 2017-07-03 [InstanceEdit:9011720] Jupe, Steve, 2017-07-05 [InstanceEdit:9015193] Duenas, Corina, 2017-08-09 [InstanceEdit:9017587] Duenas, Corina, 2017-08-22 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1 Shc1 is phosphorylated by Il15ra:Il15:Il2rb:Jak1:Il2rg:p-Jak3:Shc1
output	[Complex:8983186] Il15:Il15ra:p-Y-Il2rb:p-Y-Il2rg:p-Y-Jak1:p-Y-Jak3:p-Y-Shc [plasma membrane] [Mus musculus] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[BlackBoxEvent:8983313] Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 binds Shc1 [Mus musculus]
releaseDate	2017-09-12
reviewed	[InstanceEdit:9014997] Patidar, Manoj, 2017-08-07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:8983315] R-MMU-8983294.2
summation	[Summation:8983305] Interleukin-15 (Il15) stimulates the phosphorylation of Shc...
(inferredFrom)	[BlackBoxEvent:8983309] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates SHC1 [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:8983356] Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1 binds Grb2 [Mus musculus]
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No pathways have been reviewed or authored by Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1 (8983294)