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Details on Person PTK2B is phosphorylated by IL7:IL7R:JAK1:FYN:PTK2B

Class:Id	BlackBoxEvent:8983080
_displayName	PTK2B is phosphorylated by IL7:IL7R:JAK1:FYN:PTK2B
_doRelease	FALSE
_timestamp	2017-11-15 09:48:26
authored	[InstanceEdit:9012845] Duenas, Corina, 2017-07-20
catalystActivity	[CatalystActivity:8983476] protein tyrosine kinase activity of IL7:IL7R:JAK1 [plasma membrane]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:8983062] Duenas, Corina, 2017-03-22
edited	[InstanceEdit:9014125] Duenas, Corina, 2017-07-26
inferredFrom	[BlackBoxEvent:8983075] Ptk2b is phosphorylated [Mus musculus]
input	[SimpleEntity:113592] ATP [cytosol] [Complex:8982920] IL7:IL7R:JAK1 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8982793] Interleukin (IL)-7 induces rapid activation of Pyk2, which is bound to Janus kinase 1 and IL-7Ralpha.
modified	[InstanceEdit:8983468] Jupe, Steve, 2017-03-23 [InstanceEdit:8983477] Jupe, Steve, 2017-03-24 [InstanceEdit:9014123] Duenas, Corina, 2017-07-26 [InstanceEdit:9014125] Duenas, Corina, 2017-07-26 [InstanceEdit:9015191] Duenas, Corina, 2017-08-09 [InstanceEdit:9025936] Jupe, Steve, 2017-10-16 [InstanceEdit:9029255] Jupe, Steve, 2017-11-15
name	PTK2B is phosphorylated by IL7:IL7R:JAK1:FYN:PTK2B PTK2B is phosphorylated IL7:IL7R:JAK1:PTK2B is phosphorylated PYK2 complex is phosphorylated
output	[SimpleEntity:29370] ADP [cytosol] [Complex:8982932] IL7:IL7R:JAK1:p-PTK2B [plasma membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:8983021] IL7R:JAK1 binds PTK2B [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8983099] R-HSA-8983080.1
summation	[Summation:8982811] Inferred from mouse: Interleukin-7 (IL7) has been observed t...
(hasEvent)	[Pathway:1266695] Interleukin-7 signaling [Homo sapiens]
(precedingEvent)	[Pathway:5684996] MAPK1/MAPK3 signaling [Homo sapiens]
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No pathways have been reviewed or authored by PTK2B is phosphorylated by IL7:IL7R:JAK1:FYN:PTK2B (8983080)