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Details on Person PKC binds active G alpha (z)

Class:Id	Reaction:8982703
_displayName	PKC binds active G alpha (z)
_doRelease	TRUE
_timestamp	2017-07-11 09:40:25
authored	[InstanceEdit:749459] Jupe, S, 2010-05-18
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:8982708] Varusai, Thawfeek, 2017-03-22
edited	[InstanceEdit:9005907] Jupe, Steve, 2017-05-11
inferredFrom	[Reaction:8982704] PKC (cow) binds G alpha z (rat) [Bos taurus]
input	[Complex:392003] G-protein alpha (z):GTP [plasma membrane] [Homo sapiens] [CandidateSet:804920] Protein kinase C conventional and novel isoforms [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:751038] Phosphorylation of Gz in human platelets. Selectivity and site of modification [LiteratureReference:8982701] Phosphorylation of Gz alpha by protein kinase C blocks interaction with the beta gamma complex
modified	[InstanceEdit:8982722] Varusai, Thawfeek, 2017-03-22 [InstanceEdit:9006074] Jupe, Steve, 2017-05-12 [InstanceEdit:9012089] Varusai, Thawfeek, 2017-07-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PKC binds active G alpha (z)
output	[Complex:8982710] G-alpha(z):GTP:PKC [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:751024] The Ligand:GPCR:Gz complex dissociates [Homo sapiens] [Reaction:749453] Liganded Gz-activating GPCR acts as a GEF for Gz [Homo sapiens]
releaseDate	2017-06-12
reviewed	[InstanceEdit:782850] D'Eustachio, P, 2010-05-21
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:9012014] Varusai, Thawfeek, 2017-07-10
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8982714] R-HSA-8982703.3
summation	[Summation:8982702] G alpha z (Lounsbury et al. 1991) and G alpha 12 (Kozasa & G...
(hasEvent)	[Pathway:418597] G alpha (z) signalling events [Homo sapiens]
(precedingEvent)	[Reaction:751040] PKC phosphorylates G alpha (z) [Homo sapiens]
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No pathways have been reviewed or authored by PKC binds active G alpha (z) (8982703)