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Details on Person Diagram of Pentose phosphate pathway (hexose monophosphate shunt), RPIA deficiency: failed conversion of R5P to RU5P, RPIA deficiency: failed conversion of RU5P to R5P, TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P, and TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P
| Class:Id | PathwayDiagram:8982671 |
|---|---|
| _displayName | Diagram of Pentose phosphate pathway (hexose monophosphate shunt), RPIA deficiency: failed conversion of R5P to RU5P, RPIA deficiency: failed conversion of RU5P to R5P, TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P, and TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P |
| _timestamp | 2025-01-06 10:16:26 |
| created | [InstanceEdit:8982677] D'Eustachio, Peter, 2017-03-21 |
| height | 942 |
| modified | [InstanceEdit:8982678] D'Eustachio, Peter, 2017-03-21 [InstanceEdit:8982681] D'Eustachio, Peter, 2017-03-21 [InstanceEdit:8983464] D'Eustachio, Peter, 2017-03-23 [InstanceEdit:9034630] D'Eustachio, Peter, 2018-01-08 [InstanceEdit:9925926] D'Eustachio, Peter, 2024-10-28 [InstanceEdit:9934059] Stephan, Ralf, 2025-01-06 [InstanceEdit:9934069] Stephan, Ralf, 2025-01-06 [InstanceEdit:9934070] Stephan, Ralf, 2025-01-06 [InstanceEdit:9934071] Stephan, Ralf, 2025-01-06 [InstanceEdit:9934073] Stephan, Ralf, 2025-01-06 |
| representedPathway | [Pathway:71336] Pentose phosphate pathway [Homo sapiens] [Pathway:5659996] RPIA deficiency: failed conversion of R5P to RU5P [Homo sapiens] [Pathway:6791461] RPIA deficiency: failed conversion of RU5P to R5P [Homo sapiens] [Pathway:6791462] TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P [Homo sapiens] [Pathway:6791055] TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P [Homo sapiens] |
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points="1533 556" /> </Catalysts> <Properties> <displayName>D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="519" reactomeId="71335" points="1455 691, 1531 693, 1679 698" position="1531 693" lineWidth="1.0"> <Inputs> <Input id="506" points="1727 539, 1672 665" /> <Input id="487" points="1150 555, 1253 689" /> </Inputs> <Outputs> <Output id="497" points="1450 641" /> <Output id="511" points="1738 657" /> </Outputs> <Catalysts> <Catalyst id="520" points="1534 756" /> </Catalysts> <Properties> <displayName>xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="523" reactomeId="163751" points="1685 731, 1552 728, 1458 726" position="1552 728" lineWidth="1.0"> <Inputs> <Input id="511" points="1746 657" /> <Input id="497" points="1450 643" /> </Inputs> <Outputs> <Output id="506" points="1711 536" /> <Output id="487" points="1147 555, 1245 726" /> </Outputs> <Catalysts> <Catalyst id="520" points="1541 756" /> </Catalysts> <Properties> <displayName>D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="528" reactomeId="71306" points="989 519, 1080 464, 1168 390" position="1080 464" lineWidth="1.0"> <Inputs> <Input id="481" /> </Inputs> <Outputs> <Output id="493" /> </Outputs> <Catalysts> <Catalyst id="529" points="1063 405" /> </Catalysts> <Properties> <displayName>RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="532" reactomeId="177784" points="1163 384, 1050 456, 981 519" position="1050 456" lineWidth="1.0"> <Inputs> <Input id="493" /> </Inputs> <Outputs> <Output id="481" /> </Outputs> <Catalysts> <Catalyst id="529" points="1059 405" /> </Catalysts> <Properties> <displayName>RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1780" reactomeId="6787329" points="1045 235, 1046 290, 1163 359" position="1046 290" lineWidth="1.0"> <Inputs> <Input id="2734" /> </Inputs> <Outputs> <Output id="493" /> </Outputs> <Catalysts> <Catalyst id="1784" points="1001 289" /> </Catalysts> <Properties> <displayName>PGM2:Mg2+ isomerises R1P to R5P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1786" reactomeId="6787321" points="1269 808, 1305 808, 1341 808" position="1305 808" lineWidth="1.0"> <Inputs> <Input id="1787" /> </Inputs> <Outputs> <Output id="1789" points="1378 809" /> <Output id="497" points="1414 653" /> </Outputs> <Catalysts> <Catalyst id="1790" points="1305 843" /> </Catalysts> <Properties> <displayName>DERA cleaves dR5P to GA3P and CH3CHO</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2592" reactomeId="8955844" points="730 333, 777 333, 822 333" position="777 333" lineWidth="1.0"> <Inputs> <Input id="2593" points="683 356" /> <Input id="2594" points="688 309" /> </Inputs> <Outputs> <Output id="493" points="1163 369" /> <Output id="2595" points="844 312" /> <Output id="2916" points="838 357" /> </Outputs> <Catalysts> <Catalyst id="2596" points="778 385" /> </Catalysts> <Properties> <displayName>RBKS phosphorylates ribose to R5P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2604" reactomeId="8959719" points="1573 338, 1573 378, 1574 410" position="1573 378" lineWidth="1.0"> <Inputs> <Input id="2605" points="1573 304" /> <Input id="2606" points="1601 319" /> </Inputs> <Outputs> <Output id="2674" points="1618 412" /> <Output id="494" points="1439 503" /> <Output id="2611" points="1623 446" /> </Outputs> <Catalysts> <Catalyst id="2609" points="1620 378" /> </Catalysts> <Properties> <displayName>SHPK phosphorylates Sedo to Sedo7P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2780" reactomeId="8982667" points="1151 807, 1183 807, 1214 807" position="1183 807" lineWidth="1.0"> <Inputs> <Input id="2781" /> </Inputs> <Outputs> <Output id="1787" /> </Outputs> <Catalysts> <Catalyst id="2895" points="1183 843" /> </Catalysts> <Properties> <displayName>PGM2:Mg2+ isomerises dR1P to dR5P</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2782" reactomeId="73580" points="1236 257, 1302 257, 1370 257" position="1302 257" lineWidth="1.0"> <Inputs> <Input id="2783" points="1191 226" /> <Input id="493" points="1192 354" /> </Inputs> <Outputs> <Output id="2784" points="1501 244" /> <Output id="2785" points="1441 210" /> <Output id="3264" points="1445 294" /> </Outputs> <Catalysts> <Catalyst id="2786" points="1302 232" /> </Catalysts> <Activators> <Activator id="2897" points="1233 226" /> <Activator id="2896" points="1369 224" /> </Activators> <Properties> <displayName>PRPS dimers pyrophosphorylate R5P using ATP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="2798" reactomeId="111215" points="1231 114, 1300 114, 1366 113, 1532 127" position="1300 114" lineWidth="1.0"> <Inputs> <Input id="493" points="1180 354, 1106 148" /> <Input id="2799" points="1195 138" /> </Inputs> <Outputs> <Output id="2800" points="1492 143" /> <Output id="2784" points="1527 224" /> <Output id="3264" points="1469 285" /> </Outputs> <Catalysts> <Catalyst id="2801" points="1300 144" /> </Catalysts> <Activators> <Activator id="2896" points="1392 194, 1373 139" /> <Activator id="2897" points="1220 203, 1243 138" /> </Activators> <Properties> <displayName>PRPS1 dimer pyrophosphorylates R5P using dATP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="2802" points="1300 172, 1301 185" position="1300 178" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="2801" /> </Inputs> <Outputs> <Output id="2786" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableInteraction id="3268" interactionType="Activate" points="129 263, 127 518" position="128 390" lineWidth="2.0"> <Inputs> <Input id="3267" /> </Inputs> <Outputs> <Output id="80" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.RenderableInteraction id="3270" interactionType="Activate" points="802 812, 1098 808" position="950 810" lineWidth="2.0"> <Inputs> <Input id="3269" /> </Inputs> <Outputs> <Output id="2781" /> </Outputs> </org.gk.render.RenderableInteraction> </Edges> <Pathways /> </Process> |
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No pathways have been reviewed or authored by Diagram of Pentose phosphate pathway (hexose monophosphate shunt), RPIA deficiency: failed conversion of R5P to RU5P, RPIA deficiency: failed conversion of RU5P to R5P, TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P, and TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P (8982671)
