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Details on Person G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3

Class:Id	Reaction:8982012
_displayName	G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3
_doRelease	TRUE
_timestamp	2018-09-03 14:59:45
authored	[InstanceEdit:9014287] Varusai, Thawfeek, 2017-07-27
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:8982022] Varusai, Thawfeek, 2017-03-15
edited	[InstanceEdit:9014287] Varusai, Thawfeek, 2017-07-27
input	[Complex:8982015] G alpha (i):GDP:RGS [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8949498] Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits [LiteratureReference:8982372] Regulators of G-protein signalling as new central nervous system drug targets
modified	[InstanceEdit:8982300] Varusai, Thawfeek, 2017-03-17 [InstanceEdit:8982369] Varusai, Thawfeek, 2017-03-17 [InstanceEdit:9014394] Varusai, Thawfeek, 2017-07-28 [InstanceEdit:9016695] Varusai, Thawfeek, 2017-08-15 [InstanceEdit:9618031] Varusai, Thawfeek, 2018-09-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3
output	[DefinedSet:8982016] RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] [Homo sapiens] [Complex:392164] G-protein alpha (i):GDP [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:8982020] G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated [Homo sapiens] [Reaction:8982019] Active G alpha (i)–i1/i2/i3 binds RGS proteins [Homo sapiens]
releaseDate	2018-12-13
reviewed	[InstanceEdit:9618033] Siderovski, David, 2018-09-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8982034] R-HSA-8982012.2
summation	[Summation:8982298] G Protein Coupled Receptors (GPCR) sense extracellular signa...
(hasEvent)	[Pathway:418594] G alpha (i) signalling events [Homo sapiens]
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No pathways have been reviewed or authored by G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (8982012)