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Details on Person TRAF3IP2 binds IL17C:IL17CReceptor complex

Class:Id	Reaction:8980460
_displayName	TRAF3IP2 binds IL17C:IL17CReceptor complex
_doRelease	FALSE
_timestamp	2017-08-14 13:47:11
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:7660] nucleoplasm
created	[InstanceEdit:8980459] Duenas, Corina, 2017-02-27
inferredFrom	[BlackBoxEvent:8980461] Traf3ip2 binds Il17c:Il17c Receptor complex [Mus musculus]
input	[EntityWithAccessionedSequence:8979712] TRAF3IP2 [cytosol] [Homo sapiens] [Complex:6787823] IL17C dimer:IL17RA:IL17RE [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8980108] Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E [LiteratureReference:5678541] IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens
modified	[InstanceEdit:9015115] Duenas, Corina, 2017-08-08 [InstanceEdit:9016491] Duenas, Corina, 2017-08-14
name	TRAF3IP2 binds IL17C:IL17CReceptor complex
output	[Complex:8980176] IL17C dimer:IL17RA:IL17RE:TRAF3IP2 [plasma membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:5678544] IL17RA:IL17RE binds IL17C dimer [Homo sapiens] [BlackBoxEvent:8951069] IL17C dimer translocates from cytosol to extracellular region [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8980463] R-HSA-8980460.1
summation	[Summation:8980117] Inferred from mouse: Adapter protein CIKS (TRAF3IP2 or A...
(hasEvent)	[Pathway:448424] Interleukin-17 signaling [Homo sapiens]
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No pathways have been reviewed or authored by TRAF3IP2 binds IL17C:IL17CReceptor complex (8980460)