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Details on Person Adapter protein CIKS (TRAF3IP2 or Act1) binds to the Interle...

Class:Id	Summation:8980085
_displayName	Adapter protein CIKS (TRAF3IP2 or Act1) binds to the Interle...
_timestamp	2017-04-25 13:53:33
created	[InstanceEdit:8980086] Duenas, Corina, 2017-02-27
literatureReference	[LiteratureReference:8980108] Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E [LiteratureReference:5678541] IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens
modified	[InstanceEdit:8983963] Duenas, Corina, 2017-03-31 [InstanceEdit:8986314] Duenas, Corina, 2017-04-25
text	Adapter protein CIKS (TRAF3IP2 or Act1) binds to the Interleukin-17C (IL17C) - Interleukin-25(IL25 or IL17RE) dimer and it is neccesary for the downstream signaling (Chang et al.2011). Moreover IL17C after interact with its receptor promote Nuclear factor kappaB signaling and MAPK signaling (Song et al. 2011)
(summation)	[BlackBoxEvent:8980461] Traf3ip2 binds Il17c:Il17c Receptor complex [Mus musculus]
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