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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Diagram of Triglyceride metabolism

Class:IdPathwayDiagram:8979223
_displayNameDiagram of Triglyceride metabolism
_timestamp2025-07-18 19:07:54
created[InstanceEdit:8979225] D'Eustachio, Peter, 2017-02-22
height939
modified[InstanceEdit:8980655] D'Eustachio, Peter, 2017-02-28
[InstanceEdit:8980656] D'Eustachio, Peter, 2017-02-28
[InstanceEdit:9005967] D'Eustachio, Peter, 2017-05-11
[InstanceEdit:9958494] D'Eustachio, Peter, 2025-06-20
[InstanceEdit:9961065] D'Eustachio, Peter, 2025-07-18
representedPathway[Pathway:8979227] Triglyceride metabolism [Homo sapiens]
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<displayName>AGMO cleaves alkylglycerol into fatty aldehyde and glycerol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="19" reactomeId="75887" points="466 136, 500 136, 501 171" position="500 136" lineWidth="1.0"> <Inputs> <Input id="20" points="435 111" /> <Input id="14" points="355 136" /> </Inputs> <Outputs> <Output id="21" points="501 213" /> <Output id="22" points="542 187" /> </Outputs> <Catalysts> <Catalyst id="23" points="542 109" /> </Catalysts> <Properties> <displayName>Conversion of Glycerol to Glycerol-3-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="24" reactomeId="75886" points="501 289, 502 324, 503 364" position="502 324" lineWidth="1.0"> <Inputs> <Input id="21" points="501 249" /> <Input id="25" points="531 275" /> </Inputs> <Outputs> <Output id="26" points="530 376" /> <Output id="27" points="502 417" /> </Outputs> <Catalysts> <Catalyst id="28" points="613 321" /> </Catalysts> <Properties> <displayName>glycerol 3-phosphate + acyl-CoA =&gt; 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated]</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="32" reactomeId="75899" points="502 524, 502 551, 502 577" position="502 551" lineWidth="1.0"> <Inputs> <Input id="33" points="502 498" /> <Input id="34" points="545 511" /> </Inputs> <Outputs> <Output id="35" points="502 608" /> <Output id="36" points="553 588" /> </Outputs> <Catalysts> <Catalyst id="37" points="426 549" /> </Catalysts> <Properties> <displayName>1,2-diacyl-glycerol 3-phosphate + H2O =&gt; 1,2-diacyl-glycerol + orthophosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="41" reactomeId="6800334" points="614 743, 613 698, 612 657" position="613 698" lineWidth="1.0"> <Inputs> <Input id="42" points="602 751" /> <Input id="43" points="615 790" /> </Inputs> <Outputs> <Output id="35" points="527 632" /> <Output id="26" points="576 408, 612 452" /> </Outputs> <Catalysts> <Catalyst id="44" points="408 698" /> </Catalysts> <Properties> <displayName>MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="48" reactomeId="75900" points="503 681, 504 755, 505 788" position="504 755" lineWidth="1.0"> <Inputs> <Input id="35" points="502 644" /> <Input id="51" points="475 668" /> </Inputs> <Outputs> <Output id="49" points="508 848" /> <Output id="52" points="460 824" /> </Outputs> <Catalysts> <Catalyst id="50" points="420 751" /> </Catalysts> <Properties> <displayName>1,2-diacyl-glycerol + acyl-CoA =&gt; triacylglycerol + CoASH [DGAT1]</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="56" reactomeId="549192" points="526 672, 529 776, 528 812" position="529 776" lineWidth="1.0"> <Inputs> <Input id="35" points="509 644" /> <Input id="51" points="475 661" /> </Inputs> <Outputs> <Output id="49" points="514 848" /> <Output id="52" points="478 830" /> </Outputs> <Catalysts> <Catalyst id="57" points="410 790" /> </Catalysts> <Properties> <displayName>1,2-diacyl-glycerol + acyl-CoA =&gt; triacylglycerol + CoASH [DGAT2]</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="73" reactomeId="188467" points="850 322, 851 355, 852 383" position="851 355" lineWidth="1.0"> <Inputs> <Input id="74" points="877 299" /> <Input id="75" points="830 299" /> </Inputs> <Outputs> <Output id="77" points="829 412" /> <Output id="76" points="879 412" /> </Outputs> <Catalysts> <Catalyst id="78" points="907 354" /> </Catalysts> <Properties> <displayName>Gly-3-P+FAD-&gt;DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase)</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="82" reactomeId="163416" points="1051 135, 1050 165, 1050 194" position="1050 165" lineWidth="1.0"> <Inputs> <Input id="83" points="1050 108" /> <Input id="84" stoichiometry="2" points="1108 98" /> </Inputs> <Outputs> <Output id="85" stoichiometry="2" points="1111 236" /> <Output id="86" points="1050 246" /> </Outputs> <Catalysts> <Catalyst id="87" points="1091 164" /> </Catalysts> <Properties> <displayName>hormone-sensitive lipase (HSL) + 2 ATP -&gt; phosphorylated HSL + 2 ADP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="88" reactomeId="163602" points="1050 286, 1050 335, 1050 369" position="1050 335" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="86" stoichiometry="2" /> </Inputs> <Outputs> <Output id="89" /> </Outputs> <Properties> <displayName>2 phosphorylated HSL monomers -&gt; phosphorylated HSL dimer</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="90" reactomeId="163539" points="1437 98, 1401 98, 1369 98" position="1401 98" lineWidth="1.0" reactionType="Dissociation"> <Inputs> <Input id="91" /> </Inputs> <Outputs> <Output id="92" points="1334 98" /> <Output id="93" points="1350 61" /> </Outputs> <Properties> <displayName>perilipin:ABHD5 complex -&gt; perilipin + ABHD5</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="94" reactomeId="163418" points="1309 140, 1309 165, 1310 224" position="1309 165" lineWidth="1.0"> <Inputs> <Input id="92" points="1309 112" /> <Input id="84" stoichiometry="2" points="1154 92" /> </Inputs> <Outputs> <Output id="97" points="1310 279" /> <Output id="85" stoichiometry="2" points="1158 246" /> </Outputs> <Catalysts> <Catalyst id="87" points="1169 164" /> </Catalysts> <Activators> <Activator id="98" points="1355 165" /> </Activators> <Properties> <displayName>perilipin + 2 ATP -&gt; phosphorylated perilipin + 2 ADP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="99" reactomeId="163554" points="1103 392, 1310 392, 1415 393" position="1310 392" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="89" /> </Inputs> <Outputs> <Output id="100" /> </Outputs> <Properties> <displayName>Phosphorylated HSL dimer translocates from the cytosol to the lipid particle</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="101" reactomeId="163549" points="1475 445, 1476 475, 1477 508" position="1476 475" lineWidth="1.0" reactionType="Transition"> <Inputs> <Input id="100" points="1474 415" /> <Input id="102" points="1520 435" /> </Inputs> <Outputs> <Output id="103" /> </Outputs> <Catalysts> <Catalyst id="102" points="1545 444, 1545 475" /> </Catalysts> <Properties> <displayName>phosphorylated HSL dimer + FABP4 -&gt; phosphorylated HSL dimer:FABP4 complex</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="107" reactomeId="163432" points="1310 498, 1310 536, 1309 571" position="1310 536" lineWidth="1.0"> <Inputs> <Input id="108" points="1281 472" /> <Input id="109" points="1341 477" /> </Inputs> <Outputs> <Output id="115" points="1171 726, 1225 605" /> <Output id="110" points="1336 591" /> <Output id="179" points="1243 548" /> </Outputs> <Catalysts> <Catalyst id="103" points="1415 536" /> </Catalysts> <Properties> <displayName>cholesterol ester + H2O -&gt; cholesterol + fatty acid</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="122" reactomeId="163551" points="1372 502, 1372 521, 1374 562" position="1372 521" lineWidth="1.0"> <Inputs> <Input id="124" points="1405 478" /> <Input id="108" points="1292 463" /> </Inputs> <Outputs> <Output id="115" points="1174 726, 1243 617" /> <Output id="125" points="1414 607" /> <Output id="179" points="1243 545" /> </Outputs> <Catalysts> <Catalyst id="103" points="1415 527" /> </Catalysts> <Properties> <displayName>triacylglycerol + H2O -&gt; diacylglycerol + fatty acid</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="126" reactomeId="163402" points="1428 661, 1429 686, 1428 714" position="1429 686" lineWidth="1.0"> <Inputs> <Input id="127" points="1291 642" /> <Input id="125" points="1427 643" /> </Inputs> <Outputs> <Output id="128" points="1428 737" /> <Output id="115" points="1197 742" /> <Output id="178" points="1257 705" /> </Outputs> <Catalysts> <Catalyst id="103" points="1478 566, 1481 687" /> </Catalysts> <Properties> <displayName>diacylglycerol + H2O -&gt; 2-acylglycerol + fatty acid</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="130" reactomeId="163595" points="1350 775, 1351 798, 1351 825" position="1351 798" lineWidth="1.0"> <Inputs> <Input id="128" points="1377 767" /> <Input id="127" points="1275 658" /> </Inputs> <Outputs> <Output id="115" points="1197 758" /> <Output id="178" points="1250 724" /> <Output id="134" points="1285 853" /> </Outputs> <Catalysts> <Catalyst id="132" points="1388 798" /> </Catalysts> <Properties> <displayName>2-acylglycerol + H2O -&gt; glycerol + fatty acid</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="135" reactomeId="5334794" points="1138 787, 1139 816, 1139 854" position="1139 816" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="115" points="1152 767" /> <Input id="136" points="1114 774" /> </Inputs> <Outputs> <Output id="137" /> </Outputs> <Catalysts> <Catalyst id="136" points="1080 781, 1080 815" /> </Catalysts> <Properties> <displayName>FABPs bind LCFAs</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="141" reactomeId="163489" points="997 182, 996 145, 994 110" position="996 145" lineWidth="1.0"> <Inputs> <Input id="86" points="1039 246" /> <Input id="142" points="976 189" /> </Inputs> <Outputs> <Output id="83" points="1031 98" /> <Output id="144" points="964 99" /> </Outputs> <Properties> <displayName>phosphorylated HSL + H2O -&gt; HSL + orthophosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="145" reactomeId="163568" points="1332 245, 1332 201, 1332 149" position="1332 201" lineWidth="1.0"> <Inputs> <Input id="146" points="1243 277" /> <Input id="97" points="1319 279" /> </Inputs> <Outputs> <Output id="92" points="1314 112" /> <Output id="149" points="1248 90" /> </Outputs> <Catalysts> <Catalyst id="147" points="1270 198" /> </Catalysts> <Properties> <displayName>phosphorylated perilipin + H2O -&gt; perilipin + orthophosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="159" reactomeId="8848338" points="1018 571, 1020 601, 1021 652" position="1020 601" lineWidth="1.0"> <Inputs> <Input id="160" points="1065 545" /> <Input id="165" points="1016 542" /> </Inputs> <Outputs> <Output id="115" points="1137 726" /> <Output id="163" points="1014 727" /> <Output id="189" points="1060 702" /> </Outputs> <Catalysts> <Catalyst id="161" points="900 599" /> </Catalysts> <Properties> <displayName>PNPLA4 hydrolyzes TAG</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="166" reactomeId="8848355" points="942 576, 943 643, 944 677" position="943 643" lineWidth="1.0"> <Inputs> <Input id="167" points="915 541" /> <Input id="160" points="1065 540" /> </Inputs> <Outputs> <Output id="169" points="914 688" /> <Output id="170" points="945 711" /> <Output id="189" points="1051 713" /> </Outputs> <Catalysts> <Catalyst id="161" points="889 615" /> </Catalysts> <Inhibitors> <Inhibitor id="171" points="885 651" /> </Inhibitors> <Properties> <displayName>PNPLA4 hydrolyzes retinyl palmitate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="175" reactomeId="8848339" points="1067 579, 1069 609, 1071 654" position="1069 609" lineWidth="1.0"> <Inputs> <Input id="160" points="1082 552" /> <Input id="165" points="1029 542" /> </Inputs> <Outputs> <Output id="115" points="1146 726" /> <Output id="163" points="1022 727" /> <Output id="189" points="1071 702" /> </Outputs> <Catalysts> <Catalyst id="177" points="1105 610" /> </Catalysts> <Properties> <displayName>PNPLA5 hydrolyzes TAG</displayName> </Properties> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process>
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No pathways have been reviewed or authored by Diagram of Triglyceride metabolism (8979223)
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