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Details on Person Diagram of Mitochondrial Fatty Acid Beta-Oxidation and Diseases of mitochondrial beta oxidation

Class:IdPathwayDiagram:8979029
_displayNameDiagram of Mitochondrial Fatty Acid Beta-Oxidation and Diseases of mitochondrial beta oxidation
_timestamp2025-12-29 22:36:47
created[InstanceEdit:8979027] D'Eustachio, Peter, 2017-02-20
height1492
modified[InstanceEdit:8979079] D'Eustachio, Peter, 2017-02-21
[InstanceEdit:9037818] D'Eustachio, Peter, 2018-02-21
[InstanceEdit:9038428] D'Eustachio, Peter, 2018-02-26
[InstanceEdit:9644174] D'Eustachio, Peter, 2019-04-09
[InstanceEdit:9645116] Wu, G, 2019-05-03
[InstanceEdit:9697716] Jassal, Bijay, 2020-08-20
[InstanceEdit:9759776] D'Eustachio, Peter, 2021-12-13
[InstanceEdit:9815406] D'Eustachio, Peter, 2022-08-17
[InstanceEdit:9855460] Stephan, Ralf, 2023-12-03
[InstanceEdit:9855461] Stephan, Ralf, 2023-12-03
[InstanceEdit:9939423] D'Eustachio, Peter, 2025-02-26
[InstanceEdit:9939572] Matthews, Lisa, 2025-03-03
[InstanceEdit:9977441] D'Eustachio, Peter, 2025-12-19
[InstanceEdit:9977654] D'Eustachio, Peter, 2025-12-22
[InstanceEdit:9977727] D'Eustachio, Peter, 2025-12-22
[InstanceEdit:9978231] D'Eustachio, Peter, 2025-12-29
[InstanceEdit:9978272] D'Eustachio, Peter, 2025-12-29
representedPathway[Pathway:77289] Mitochondrial Fatty Acid Beta-Oxidation [Homo sapiens]
[Pathway:9759774] Diseases of mitochondrial beta oxidation [Homo sapiens]
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666" bounds="422 651 68 30" textPosition="429 655" /> <org.gk.render.RenderableChemical id="216" reactomeId="113559" position="273 671" bounds="239 656 68 30" textPosition="247 660"> <Properties> <displayName>Ac-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="217" reactomeId="77313" position="326 838" bounds="275 823 103 30" textPosition="280 827"> <Properties> <displayName>Crotonoyl-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="218" reactomeId="77316" position="340 792" bounds="310 776 60 33" textPosition="311 773" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ACADS tetramer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="219" reactomeId="113596" position="325 746" bounds="304 731 42 30" textPosition="309 735" /> <org.gk.render.RenderableChemical id="220" reactomeId="31649" position="237 863" bounds="207 848 60 30" textPosition="213 852" /> <org.gk.render.RenderableChemical id="221" reactomeId="113521" position="391 877" bounds="370 862 42 30" textPosition="374 866" /> <org.gk.render.RenderableChemical id="222" reactomeId="77251" position="481 834" bounds="443 819 77 30" textPosition="450 823"> <Properties> <displayName>3HB-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="223" reactomeId="71048" position="426 767" bounds="393 749 66 36" textPosition="396 749" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ECHS1 hexamer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="224" reactomeId="73871" position="752 832" bounds="714 817 77 30" textPosition="721 821"> <Properties> <displayName>ACA-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="225" reactomeId="113526" position="497 794" bounds="472 779 51 30" textPosition="475 783" /> <org.gk.render.RenderableChemical id="226" reactomeId="113529" position="627 794" bounds="610 779 34 30" textPosition="613 783" /> <org.gk.render.RenderableChemical id="227" reactomeId="29362" position="678 802" bounds="653 787 51 30" textPosition="657 791" /> <org.gk.render.RenderableChemical id="228" reactomeId="77359" position="191 1293" bounds="157 1278 68 30" textPosition="163 1282"> <Properties> <displayName>LIN-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="229" reactomeId="113521" position="319 1247" bounds="298 1232 42 30" textPosition="302 1236" /> <org.gk.render.RenderableChemical id="230" reactomeId="77358" position="581 1289" bounds="521 1260 120 58" textPosition="531 1264"> <Properties> <displayName>cis,cis-3,6-Dodecadienoyl-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="231" reactomeId="77267" position="343 1200" bounds="301 1183 85 34" textPosition="302 1181" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableChemical id="232" reactomeId="31649" position="494 1359" bounds="464 1344 60 30" textPosition="470 1348"> <Properties> <displayName>FADH2</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="233" reactomeId="113596" position="236 1332" bounds="215 1317 42 30" textPosition="220 1321" /> <org.gk.render.RenderableChemical id="234" reactomeId="29374" position="221 1241" bounds="187 1226 68 30" textPosition="194 1230" /> <org.gk.render.RenderableChemical id="235" reactomeId="113559" position="488 1243" bounds="454 1228 68 30" textPosition="462 1232" /> <org.gk.render.RenderableChemical id="236" reactomeId="113529" position="426 1353" bounds="409 1338 34 30" textPosition="412 1342" /> <org.gk.render.RenderableChemical id="237" reactomeId="29362" position="570 1349" bounds="545 1334 51 30" textPosition="549 1338" /> <org.gk.render.RenderableComplex id="238" reactomeId="77258" position="455 1197" bounds="402 1186 107 22" textPosition="405 1186" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableChemical id="239" reactomeId="113526" position="341 1333" bounds="316 1318 51 30" textPosition="319 1322"> <Properties> <displayName>NAD+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="240" reactomeId="77360" position="578 1115" bounds="510 1093 137 44" textPosition="514 1097"> <Properties> <displayName>trans,cis-Lauro-2,6-dienoyl-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="241" reactomeId="110060" position="585 930" bounds="559 913 53 35" textPosition="564 912" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>DCI dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="242" reactomeId="113521" position="512 1069" bounds="491 1054 42 30" textPosition="495 1058" /> <org.gk.render.RenderableChemical id="243" reactomeId="109986" position="216 1122" bounds="152 1100 129 44" textPosition="153 1111"> <Properties> <displayName>4-cis-decenoyl-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="244" reactomeId="113559" position="279 1069" bounds="245 1054 68 30" textPosition="253 1058" /> <org.gk.render.RenderableChemical id="245" reactomeId="113529" position="335 1155" bounds="318 1140 34 30" textPosition="321 1144" /> <org.gk.render.RenderableChemical id="246" reactomeId="29362" position="252 1184" bounds="227 1169 51 30" textPosition="231 1173" /> <org.gk.render.RenderableChemical id="247" reactomeId="113526" position="533 1163" bounds="508 1148 51 30" textPosition="511 1152" /> <org.gk.render.RenderableChemical id="248" reactomeId="113596" position="471 1157" bounds="450 1142 42 30" textPosition="455 1146" /> <org.gk.render.RenderableChemical id="249" reactomeId="29374" position="436 1069" bounds="402 1054 68 30" textPosition="409 1058" /> <org.gk.render.RenderableChemical id="250" reactomeId="31649" position="360 1069" bounds="330 1054 60 30" textPosition="336 1058" /> <org.gk.render.RenderableChemical id="251" reactomeId="109990" position="215 976" bounds="151 954 129 44" textPosition="162 958"> <Properties> <displayName>2-trans-4-cis-decadienoyl-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="252" reactomeId="77335" position="133 1037" bounds="88 1021 91 32" textPosition="104 1017" bgColor="204 255 255" hideComponents="true" /> <org.gk.render.RenderableChemical id="253" reactomeId="31649" position="121 993" bounds="91 978 60 30" textPosition="97 982" /> <org.gk.render.RenderableChemical id="254" reactomeId="113596" position="124 1083" bounds="103 1068 42 30" textPosition="108 1072"> <Properties> <displayName>FAD</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="255" reactomeId="109994" position="468 991" bounds="388 969 160 44" textPosition="398 980"> <Properties> <displayName>3-trans-decenoyl-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="256" reactomeId="110061" position="325 935" bounds="290 917 70 36" textPosition="296 917" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>DECR1 tetramer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="257" reactomeId="113529" position="251 933" bounds="234 918 34 30" textPosition="237 922" /> <org.gk.render.RenderableChemical id="258" reactomeId="29362" position="270 1018" bounds="245 1003 51 30" textPosition="249 1007" /> <org.gk.render.RenderableChemical id="259" reactomeId="113526" position="400 943" bounds="375 928 51 30" textPosition="378 932" /> <org.gk.render.RenderableChemical id="272" reactomeId="70958" position="1279 1080" bounds="1237 1065 85 30" textPosition="1245 1069"> <Properties> <displayName>SUCC-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="279" reactomeId="70843" position="1277 738" bounds="1235 723 85 30" textPosition="1243 727"> <Properties> <displayName>PROP-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="282" reactomeId="113548" position="1330 866" bounds="1318 851 25 30" textPosition="1321 855"> <Properties> <displayName>Pi</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="283" reactomeId="71019" position="1277 893" bounds="1235 878 85 30" textPosition="1241 882"> <Properties> <displayName>MEMA-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="284" reactomeId="71026" position="1181 800" bounds="1118 789 126 22" textPosition="1120 789" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>6x(Btn-PCCA:PCCB)</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="285" reactomeId="71009" position="1277 990" bounds="1235 975 85 30" textPosition="1242 979"> <Properties> <displayName>L-MM-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="286" reactomeId="71012" position="1213 938" bounds="1192 927 43 22" textPosition="1193 927"> <Properties> <displayName>MCEE</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="397" reactomeId="3159272" position="1183 1030" bounds="1132 1012 103 36" textPosition="1136 1012" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>2xMMAA:2xMUT:AdoCbl</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="3220" reactomeId="5695946" position="780 1002" bounds="725 987 111 30" textPosition="734 991"> <Properties> <displayName>S-2MPDA-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3222" reactomeId="5695949" position="999 1002" bounds="939 987 120 30" textPosition="948 991"> <Properties> <displayName>S-2MDPDA-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="3224" reactomeId="5695955" position="890 1000" bounds="860 989 60 22" textPosition="861 989"> <Properties> <displayName>ACAD10</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="3226" reactomeId="5695963" position="1140 1138" bounds="1106 1123 68 30" textPosition="1113 1127"> <Properties> <displayName>BH-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="3227" reactomeId="5695976" position="1322 1205" bounds="1284 1190 77 30" textPosition="1291 1194"> <Properties> <displayName>DHB-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="3228" reactomeId="5695987" position="1366 1135" bounds="1336 1124 60 22" textPosition="1337 1124"> <Properties> <displayName>ACAD11</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="5168" reactomeId="113596" position="1191 1175" bounds="1170 1160 42 30" textPosition="1175 1164" /> <org.gk.render.RenderableChemical id="5170" reactomeId="31649" position="1273 1241" bounds="1243 1226 60 30" textPosition="1249 1230" /> <org.gk.render.RenderableChemical id="5172" reactomeId="31649" position="998 1054" bounds="968 1039 60 30" textPosition="974 1043" /> <org.gk.render.RenderableChemical id="5174" reactomeId="113596" position="802 1054" bounds="781 1039 42 30" textPosition="786 1043" /> <org.gk.render.RenderableChemical id="7389" reactomeId="1524038" position="1234 645" bounds="1204 630 61 30" textPosition="1204 634"> <Properties> <displayName>acyl-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="7390" reactomeId="8874749" position="1237 503" bounds="1205 487 65 33" textPosition="1206 492"> <Properties> <displayName>3OA-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="7391" reactomeId="8874746" position="1279 576" bounds="1249 560 61 32" textPosition="1250 556" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ACAA2 tetramer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="7938" reactomeId="113593" position="204 663" bounds="188 648 32 31" textPosition="188 652" /> <org.gk.render.RenderableChemical id="7939" reactomeId="8875042" position="168 644" bounds="152 630 33 29" textPosition="153 633"> <Properties> <displayName>BUT</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="7940" reactomeId="8875066" position="111 717" bounds="85 702 53 31" textPosition="85 700"> <Properties> <displayName>ACSM3,ACSM6</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="8009" reactomeId="159448" position="118 767" bounds="95 753 47 29" textPosition="102 756"> <Properties> <displayName>AMP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="8011" reactomeId="159450" position="172 784" bounds="155 769 34 30" textPosition="159 773"> <Properties> <displayName>PPi</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="9110" reactomeId="977314" position="1159 1325" bounds="1114 1310 90 30" textPosition="1118 1314"> <Properties> <displayName>Malonyl-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="9112" reactomeId="8933305" position="1241 1294" bounds="1220 1283 43 22" textPosition="1220 1283"> <Properties> <displayName>MCAT</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="9116" reactomeId="29374" position="1326 1314" bounds="1292 1299 68 30" textPosition="1299 1303"> <Properties> <displayName>CoA-SH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="9124" reactomeId="8934586" position="1321 1400" bounds="1262 1382 119 36" textPosition="1262 1382"> <Properties> <displayName>Mal-PPANT-S112-NDUFAB1</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.14705882352941177" relativeY="0.0" label="PN" trackId="0" reactomeId="8934585" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="9155" reactomeId="8952866" position="496 350" bounds="471 333 51 34" textPosition="474 331" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>MECR dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="9157" reactomeId="113529" position="417 379" bounds="400 364 34 30" textPosition="403 368" /> <org.gk.render.RenderableChemical id="9159" reactomeId="113600" position="435 345" bounds="406 330 59 30" textPosition="410 334"> <Properties> <displayName>NADPH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="9161" reactomeId="113563" position="571 369" bounds="541 354 60 30" textPosition="545 358"> <Properties> <displayName>NADP+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableCompartment id="9162" reactomeId="70101" position="1043 744" bounds="4 4 2078 1480" textPosition="77 1436" bgColor="250 240 240" lineColor="255 153 102" insets="16 16 2054 1457"> <Properties> <displayName>cytosol</displayName> </Properties> <Components> <Component id="117" /> <Component id="9201" /> <Component id="9203" /> <Component id="9204" /> <Component id="9205" /> <Component id="9206" /> <Component id="9226" /> <Component id="9227" /> <Component id="9228" /> <Component id="9229" /> <Component id="9230" /> <Component id="9240" /> <Component id="9202" /> <Component id="9207" /> <Component id="9362" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableChemical id="9173" reactomeId="5690531" position="772 1167" bounds="748 1152 49 30" textPosition="752 1156"> <Properties> <displayName>MCFA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="9174" reactomeId="113593" position="799 1131" bounds="780 1116 38 30" textPosition="783 1120"> <Properties> <displayName>ATP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="9175" reactomeId="5690542" position="1024 1168" bounds="984 1153 81 30" textPosition="989 1157"> <Properties> <displayName>MCFA-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="9176" reactomeId="5696005" position="903 1216" bounds="874 1206 58 21" textPosition="881 1206"> <Properties> <displayName>ACSF2</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="9178" reactomeId="159448" position="922 1119" bounds="891 1103 62 33" textPosition="905 1108" /> <org.gk.render.RenderableChemical id="9180" reactomeId="159450" position="999 1121" bounds="982 1106 34 30" textPosition="986 1110" /> <org.gk.render.RenderableChemical id="9182" reactomeId="29374" position="826 1212" bounds="792 1197 68 30" textPosition="799 1201" /> <org.gk.render.RenderableEntitySet id="9184" reactomeId="5690540" position="1023 1267" bounds="975 1248 96 38" textPosition="984 1249" /> <org.gk.render.RenderableChemical id="9186" reactomeId="113521" position="1007 1316" bounds="986 1301 43 30" textPosition="990 1305" /> <org.gk.render.RenderableEntitySet id="9187" reactomeId="5690519" position="777 1267" bounds="737 1256 81 22" textPosition="739 1256"> <Properties> <displayName>MCFA, LCFA</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="9189" reactomeId="5690051" position="890 1333" bounds="841 1309 99 49" textPosition="856 1309"> <Properties> <displayName>ACOT2,9, THEM4,5 dimer</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="9202" reactomeId="29356" position="1713 749" bounds="1692 734 43 30" textPosition="1696 738" /> <org.gk.render.RenderableEntitySet id="9203" reactomeId="5690044" position="1665 798" bounds="1623 780 85 36" textPosition="1626 780"> <Properties> <displayName>MCFA-CoA, LCFA-CoA</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="9204" reactomeId="5690064" position="1939 798" bounds="1901 787 77 22" textPosition="1901 787" /> <org.gk.render.RenderableChemical id="9205" reactomeId="76194" position="1915 845" bounds="1884 830 62 30" textPosition="1888 834" /> <org.gk.render.RenderableEntitySet id="9206" reactomeId="5690052" position="1785 860" bounds="1730 842 110 36" textPosition="1730 842"> <Properties> <displayName>Cytosolic ACOTs, THEM4</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableProtein id="9207" reactomeId="5215990" position="1785 746" bounds="1766 735 39 22" textPosition="1766 735"> <Properties> <displayName>PCTP</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="9227" reactomeId="164991" position="1529 798" bounds="1485 785 89 27" textPosition="1496 787"> <Properties> <displayName>LCFA-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="9229" reactomeId="8848243" position="1470 832" bounds="1446 821 49 22" textPosition="1446 821"> <Properties> <displayName>ACBD6</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="9230" reactomeId="8848271" position="1530 920" bounds="1475 909 111 22" textPosition="1475 909" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>ACBD6:LCFA-CoA</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableCompartment id="9240" reactomeId="17957" position="1700 1091" bounds="1450 988 501 207" textPosition="1464 1148" bgColor="250 240 240" lineColor="255 153 102" insets="1461 998 479 186"> <Properties> <displayName>endoplasmic reticulum lumen</displayName> </Properties> <Components> <Component id="9241" /> <Component id="9242" /> <Component id="9243" /> <Component id="9244" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableEntitySet id="9242" reactomeId="8848239" position="1550 1097" bounds="1508 1086 84 22" textPosition="1508 1086"> <Properties> <displayName>DBI, (ACBD7)</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="9243" reactomeId="8848288" position="1545 1040" bounds="1487 1022 117 36" textPosition="1489 1022" /> <org.gk.render.RenderableComplex id="9244" reactomeId="8848291" position="1785 1078" bounds="1727 1060 116 36" textPosition="1728 1060" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>DBI,ACBD7:MCFA-CoA,LCFA-CoA</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="9246" reactomeId="113559" position="818 907" bounds="784 892 68 30" textPosition="792 896" /> <org.gk.render.ProcessNode id="9247" reactomeId="1428517" position="979 908" bounds="907 877 144 63" textPosition="914 879"> <Properties> <displayName>Aerobic respiration and respiratory electron transport</displayName> </Properties> </org.gk.render.ProcessNode> <org.gk.render.RenderableProtein id="9260" reactomeId="163925" position="1174 1397" bounds="1142 1386 64 23" textPosition="1142 1386"> <Properties> <displayName>NDUFAB1</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.265625" relativeY="0.0" label="PN" trackId="0" reactomeId="8933548" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="9262" reactomeId="113529" position="995 109" bounds="978 94 34 30" textPosition="981 98" /> <org.gk.render.RenderableChemical id="9264" reactomeId="113529" position="109 185" bounds="92 170 34 30" textPosition="95 174" /> <org.gk.render.RenderableChemical id="9280" reactomeId="113529" position="875 263" bounds="858 248 34 30" textPosition="861 252" /> <org.gk.render.RenderableChemical id="9296" reactomeId="113529" position="582 464" bounds="565 449 34 30" textPosition="568 453" /> <org.gk.render.RenderableChemical id="9298" reactomeId="113529" position="479 607" bounds="462 592 34 30" textPosition="465 596"> <Properties> <displayName>H+</displayName> </Properties> <Shortcuts> <Shortcut id="9298" /> <Shortcut id="9333" /> <Shortcut id="9359" /> </Shortcuts> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="9310" reactomeId="113529" position="996 753" bounds="979 738 34 30" textPosition="982 742" /> <org.gk.render.RenderableChemical id="9325" reactomeId="29374" position="119 666" bounds="85 651 68 30" textPosition="92 655" /> <org.gk.render.RenderableChemical id="9327" reactomeId="113529" position="235 762" bounds="218 747 34 30" textPosition="221 751" /> <org.gk.render.RenderableChemical id="9329" reactomeId="29896" position="1334 769" bounds="1305 754 58 31" textPosition="1309 758"> <Properties> <displayName>HCO3-</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="9330" reactomeId="113593" position="1216 766" bounds="1196 751 40 31" textPosition="1200 755" /> <org.gk.render.RenderableChemical id="9331" reactomeId="113581" position="1217 856" bounds="1197 841 41 31" textPosition="1201 845" /> <org.gk.render.RenderableChemical id="9333" reactomeId="113529" position="1328 827" bounds="1311 812 34 30" textPosition="1314 816" /> <org.gk.render.RenderableChemical id="9359" reactomeId="113529" position="805 1314" bounds="788 1299 34 30" textPosition="791 1303" /> <org.gk.render.RenderableChemical id="9362" reactomeId="70106" position="1893 754" bounds="1875 739 36 31" textPosition="1879 743" /> </Nodes> <Edges> <org.gk.render.RenderableReaction id="333" reactomeId="77299" points="967 157, 936 156, 904 156" position="936 156" lineWidth="1.0"> <Inputs> <Input id="131" points="1022 128" /> <Input id="126" points="1007 158" /> <Input id="9262" points="986 127" /> </Inputs> <Outputs> <Output id="128" points="863 156" /> <Output id="130" points="861 119" /> </Outputs> <Catalysts> <Catalyst id="129" points="934 106" /> </Catalysts> <Properties> <displayName>palmitoyl-CoA+FAD =&gt; trans-Hexadec-2-enoyl-CoA+FADH2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="334" reactomeId="77301" points="740 154, 719 155, 671 149" position="719 155" lineWidth="1.0"> <Inputs> <Input id="128" points="756 155" /> <Input id="132" points="747 121" /> </Inputs> <Outputs> <Output id="133" /> </Outputs> <Catalysts> <Catalyst id="134" points="545 187, 718 187" /> </Catalysts> <Properties> <displayName>trans-Hexadec-2-enoyl-CoA+H2O =&gt; (S)-3-Hydroxyhexadecanoyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="335" reactomeId="77303" points="519 140, 498 140, 477 139" position="498 140" lineWidth="1.0"> <Inputs> <Input id="133" points="554 141" /> <Input id="135" points="540 110" /> </Inputs> <Outputs> <Output id="136" points="474 108" /> <Output id="137" points="450 139" /> <Output id="138" points="429 106" /> </Outputs> <Catalysts> <Catalyst id="134" points="498 166" /> </Catalysts> <Properties> <displayName>(S)-3-Hydroxyhexadecanoyl-CoA+NAD =&gt; 3-Oxopalmitoyl-CoA+NADH+H</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="336" reactomeId="77304" points="296 154, 280 152, 257 152" position="280 152" lineWidth="1.0"> <Inputs> <Input id="137" points="307 151" /> <Input id="141" points="310 118" /> </Inputs> <Outputs> <Output id="139" points="236 118" /> <Output id="140" points="225 152" /> </Outputs> <Catalysts> <Catalyst id="134" points="451 185, 280 179" /> </Catalysts> <Properties> <displayName>3-Oxopalmitoyl-CoA+CoA-SH =&gt; myristoyl-CoA+acetyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="337" reactomeId="77274" points="184 198, 183 222, 184 256" position="183 222" lineWidth="1.0"> <Inputs> <Input id="140" points="183 170" /> <Input id="144" points="132 161" /> <Input id="9264" points="129 187" /> </Inputs> <Outputs> <Output id="142" points="184 275" /> <Output id="145" points="154 254" /> </Outputs> <Catalysts> <Catalyst id="143" points="217 222" /> </Catalysts> <Properties> <displayName>myristoyl-CoA+FAD =&gt; trans-tetradec-2-enoyl-CoA+FADH2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="338" reactomeId="77277" points="268 297, 292 298, 312 298" position="292 298" lineWidth="1.0"> <Inputs> <Input id="142" points="253 297" /> <Input id="146" points="261 284" /> </Inputs> <Outputs> <Output id="147" /> </Outputs> <Catalysts> <Catalyst id="134" points="451 203, 292 263" /> </Catalysts> <Properties> <displayName>trans-Tetradec-2-enoyl-CoA+H2O =&gt; (S)-3-Hydroxytetradecanoyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="339" reactomeId="77283" points="473 297, 498 296, 520 296" position="498 296" lineWidth="1.0"> <Inputs> <Input id="147" points="455 297" /> <Input id="151" points="453 255" /> </Inputs> <Outputs> <Output id="148" points="563 296" /> <Output id="149" points="529 260" /> <Output id="150" points="572 263" /> </Outputs> <Catalysts> <Catalyst id="134" points="498 208" /> </Catalysts> <Properties> <displayName>(S)-3-Hydroxytetradecanoyl-CoA+NAD =&gt; 3-Oxotetradecanoyl-CoA+NADH+H</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="340" reactomeId="77271" points="719 295, 741 296, 766 296" position="741 296" lineWidth="1.0"> <Inputs> <Input id="148" points="698 295" /> <Input id="154" points="699 268" /> </Inputs> <Outputs> <Output id="152" points="794 296" /> <Output id="153" points="797 262" /> </Outputs> <Catalysts> <Catalyst id="134" points="545 195, 739 232" /> </Catalysts> <Properties> <displayName>3-Oxotetradecanoyl-CoA+CoA-SH =&gt; Lauroyl-CoA + acetyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="341" reactomeId="77263" points="907 297, 937 296, 958 297" position="937 296" lineWidth="1.0"> <Inputs> <Input id="152" points="877 297" /> <Input id="157" points="892 311" /> <Input id="9280" points="889 281" /> </Inputs> <Outputs> <Output id="155" points="983 297" /> <Output id="158" points="974 326" /> </Outputs> <Catalysts> <Catalyst id="156" points="939 270" /> </Catalysts> <Properties> <displayName>lauroyl-CoA+FAD =&gt; 2-trans-Dodecenoyl-CoA+FADH2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="342" reactomeId="77256" points="1050 342, 1051 365, 1048 399" position="1051 365" lineWidth="1.0"> <Inputs> <Input id="155" points="1050 325" /> <Input id="159" points="1128 317" /> </Inputs> <Outputs> <Output id="160" /> </Outputs> <Catalysts> <Catalyst id="161" points="1082 363" /> </Catalysts> <Properties> <displayName>2-trans-Dodecenoyl-CoA+H2O =&gt;( S)-3-Hydroxydodecanoyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="343" reactomeId="77254" points="954 425, 930 425, 908 426" position="930 425" lineWidth="1.0"> <Inputs> <Input id="160" points="979 425" /> <Input id="166" points="995 463" /> </Inputs> <Outputs> <Output id="162" points="884 425" /> <Output id="164" points="827 471" /> <Output id="165" points="876 463" /> </Outputs> <Catalysts> <Catalyst id="163" points="929 477" /> </Catalysts> <Properties> <displayName>(S)-3-Hydroxydodecanoyl-CoA+NAD =&gt; 3-Oxododecanoyl-CoA+NADH+H</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="344" reactomeId="77309" points="732 424, 711 425, 676 424" position="711 425" lineWidth="1.0"> <Inputs> <Input id="162" points="747 423" /> <Input id="169" points="781 383" /> </Inputs> <Outputs> <Output id="167" points="630 424" /> <Output id="170" points="660 404" /> </Outputs> <Catalysts> <Catalyst id="204" points="712 370" /> </Catalysts> <Properties> <displayName>3-Oxododecanoyl-CoA+CoA-SH =&gt; Decanoyl-CoA + acetyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="345" reactomeId="77345" points="528 449, 489 449, 463 448" position="489 449" lineWidth="1.0"> <Inputs> <Input id="167" points="552 442" /> <Input id="173" points="532 462" /> <Input id="9296" points="562 459" /> </Inputs> <Outputs> <Output id="171" points="431 431" /> <Output id="174" points="444 455" /> </Outputs> <Catalysts> <Catalyst id="172" points="495 498" /> </Catalysts> <Properties> <displayName>Decanoyl-CoA+FAD =&gt; trans-Dec-2-enoyl-CoA+FADH2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="346" reactomeId="77344" points="329 416, 312 416, 287 416" position="312 416" lineWidth="1.0"> <Inputs> <Input id="171" points="366 417" /> <Input id="175" points="334 425" /> </Inputs> <Outputs> <Output id="176" /> </Outputs> <Catalysts> <Catalyst id="177" points="312 379" /> </Catalysts> <Properties> <displayName>trans-Dec-2-enoyl-CoA+H2O =&gt; (S)-Hydroxydecanoyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="347" reactomeId="77342" points="217 457, 217 478, 219 503" position="217 478" lineWidth="1.0"> <Inputs> <Input id="176" points="216 451" /> <Input id="181" points="149 458" /> </Inputs> <Outputs> <Output id="178" points="213 533" /> <Output id="179" points="122 538" /> <Output id="180" points="164 504" /> </Outputs> <Catalysts> <Catalyst id="182" points="245 475" /> </Catalysts> <Properties> <displayName>(S)-Hydroxydecanoyl-CoA+NAD =&gt; 3-Oxodecanoyl-CoA+NADH+H</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="348" reactomeId="77340" points="292 568, 317 567, 339 569" position="317 567" lineWidth="1.0"> <Inputs> <Input id="178" points="277 565" /> <Input id="185" points="278 586" /> </Inputs> <Outputs> <Output id="183" points="355 568" /> <Output id="184" points="349 588" /> </Outputs> <Catalysts> <Catalyst id="168" points="320 541" /> </Catalysts> <Properties> <displayName>3-Oxodecanoyl-CoA+CoA-SH =&gt; Octanoyl-CoA + acetyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="349" reactomeId="77338" points="476 562, 503 562, 527 562" position="503 562" lineWidth="1.0"> <Inputs> <Input id="183" points="451 563" /> <Input id="187" points="451 583" /> <Input id="9298" points="478 589" /> </Inputs> <Outputs> <Output id="186" points="552 562" /> <Output id="188" points="536 586" /> </Outputs> <Catalysts> <Catalyst id="172" points="498 526" /> </Catalysts> <Properties> <displayName>Octanoyl-CoA+FAD =&gt; trans-Oct-2-enoyl-CoA+FADH2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="350" reactomeId="77333" points="672 561, 691 560, 724 560" position="691 560" lineWidth="1.0"> <Inputs> <Input id="186" points="663 561" /> <Input id="189" points="670 587" /> </Inputs> <Outputs> <Output id="190" /> </Outputs> <Catalysts> <Catalyst id="192" points="687 518" /> </Catalysts> <Properties> <displayName>trans-Oct-2-enoyl-CoA+H2O =&gt; (S)-Hydroxyoctanoyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="351" reactomeId="77331" points="859 565, 878 566, 896 566" position="878 566" lineWidth="1.0"> <Inputs> <Input id="190" points="846 563" /> <Input id="193" points="830 609" /> </Inputs> <Outputs> <Output id="191" points="928 562" /> <Output id="194" points="923 590" /> <Output id="195" points="888 614" /> </Outputs> <Catalysts> <Catalyst id="163" points="905 518, 876 536" /> </Catalysts> <Properties> <displayName>(S)-Hydroxyoctanoyl-CoA+NAD =&gt; 3-Oxooctanoyl-CoA+NADH+H</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="352" reactomeId="77329" points="1025 591, 1025 617, 1026 646" position="1025 617" lineWidth="1.0"> <Inputs> <Input id="191" points="1012 581" /> <Input id="199" points="1078 541" /> </Inputs> <Outputs> <Output id="196" points="1028 701" /> <Output id="197" points="1056 646" /> </Outputs> <Catalysts> <Catalyst id="198" points="1045 611" /> </Catalysts> <Properties> <displayName>3-Oxooctanoyl-CoA+CoA-SH =&gt; Hexanoyl-CoA + acetyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="353" reactomeId="77327" points="964 719, 940 720, 919 719" position="940 720" lineWidth="1.0"> <Inputs> <Input id="196" points="992 719" /> <Input id="203" points="973 705" /> <Input id="9310" points="981 735" /> </Inputs> <Outputs> <Output id="200" points="897 719" /> <Output id="202" points="914 704" /> </Outputs> <Catalysts> <Catalyst id="201" points="941 766" /> </Catalysts> <Properties> <displayName>Hexanoyl-CoA+FAD =&gt; trans-Hex-2-enoyl-CoA+FADH2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="354" reactomeId="77325" points="773 717, 754 719, 732 719" position="754 719" lineWidth="1.0"> <Inputs> <Input id="200" points="788 717" /> <Input id="205" points="782 691" /> </Inputs> <Outputs> <Output id="206" /> </Outputs> <Catalysts> <Catalyst id="207" points="756 745" /> </Catalysts> <Properties> <displayName>trans-Hex-2-enoyl-CoA+H2O&lt;=&gt;(S)-Hydroxyhexanoyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="355" reactomeId="77323" points="594 719, 572 720, 551 720" position="572 720" lineWidth="1.0"> <Inputs> <Input id="206" points="606 719" /> <Input id="210" points="612 685" /> </Inputs> <Outputs> <Output id="208" points="530 720" /> <Output id="211" points="535 679" /> <Output id="212" points="579 649" /> </Outputs> <Catalysts> <Catalyst id="209" points="572 764" /> </Catalysts> <Properties> <displayName>(S)-Hydroxyhexanoyl-CoA+NAD =&gt; 3-Oxohexanoyl-CoA+NADH+H</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="356" reactomeId="77321" points="383 716, 369 716, 320 716" position="369 716" lineWidth="1.0"> <Inputs> <Input id="208" points="395 716" /> <Input id="215" points="434 684" /> </Inputs> <Outputs> <Output id="213" points="278 717" /> <Output id="216" points="288 689" /> </Outputs> <Catalysts> <Catalyst id="214" points="368 687" /> </Catalysts> <Properties> <displayName>3-Oxohexanoyl-CoA+CoA-SH =&gt; Butanoyl-CoA + acetyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="357" reactomeId="77319" points="279 764, 280 791, 280 810" position="280 791" lineWidth="1.0"> <Inputs> <Input id="213" points="253 737" /> <Input id="219" points="301 754" /> <Input id="9327" points="255 762" /> </Inputs> <Outputs> <Output id="217" points="301 820" /> <Output id="220" points="249 845" /> </Outputs> <Catalysts> <Catalyst id="218" points="307 791" /> </Catalysts> <Properties> <displayName>Butanoyl-CoA+FAD =&gt; Crotonoyl-CoA+FADH2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="358" reactomeId="77314" points="393 833, 411 833, 440 833" position="411 833" lineWidth="1.0"> <Inputs> <Input id="221" points="391 859" /> <Input id="217" points="381 834" /> </Inputs> <Outputs> <Output id="222" /> </Outputs> <Catalysts> <Catalyst id="223" points="421 788" /> </Catalysts> <Properties> <displayName>Crotonoyl-CoA+H2O =&gt; (S)-3-Hydroxybutanoyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="359" reactomeId="77312" points="538 835, 574 834, 603 833" position="574 834" lineWidth="1.0"> <Inputs> <Input id="222" points="523 834" /> <Input id="225" points="512 812" /> </Inputs> <Outputs> <Output id="224" points="711 832" /> <Output id="226" points="617 812" /> <Output id="227" points="650 812" /> </Outputs> <Catalysts> <Catalyst id="209" points="573 805" /> </Catalysts> <Properties> <displayName>(S)-Hydroxybutanoyl-CoA+NAD =&gt; Acetoacetyl-CoA+NADH+H</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="360" reactomeId="109339" points="286 1295, 385 1294, 438 1295" position="385 1294" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="228" points="228 1293" /> <Input id="229" stoichiometry="3" points="308 1265" /> <Input id="233" stoichiometry="3" points="256 1314" /> <Input id="234" stoichiometry="3" points="239 1259" /> <Input id="239" stoichiometry="3" points="319 1315" /> </Inputs> <Outputs> <Output id="230" points="518 1291" /> <Output id="232" stoichiometry="3" points="480 1341" /> <Output id="235" stoichiometry="3" points="473 1261" /> <Output id="236" stoichiometry="3" points="429 1335" /> <Output id="237" stoichiometry="3" points="542 1338" /> </Outputs> <Activators> <Activator id="231" points="350 1220" /> <Activator id="238" points="447 1211" /> </Activators> <Properties> <displayName>Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="361" reactomeId="109338" points="581 1257, 581 1213, 578 1140" position="581 1213" lineWidth="1.0"> <Inputs> <Input id="230" /> </Inputs> <Outputs> <Output id="240" /> </Outputs> <Catalysts> <Catalyst id="241" points="609 951, 664 986, 668 1212" /> </Catalysts> <Properties> <displayName>Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="362" reactomeId="109342" points="479 1118, 397 1119, 336 1118" position="397 1119" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="242" points="501 1087" /> <Input id="240" points="507 1117" /> <Input id="247" points="515 1145" /> <Input id="248" points="474 1139" /> <Input id="249" points="449 1087" /> </Inputs> <Outputs> <Output id="243" points="284 1119" /> <Output id="244" points="296 1087" /> <Output id="245" points="335 1137" /> <Output id="246" points="271 1166" /> <Output id="250" points="352 1087" /> </Outputs> <Activators> <Activator id="231" points="354 1180" /> <Activator id="238" points="446 1183" /> </Activators> <Properties> <displayName>Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="363" reactomeId="109341" points="215 1064, 214 1038, 214 1019" position="214 1038" lineWidth="1.0"> <Inputs> <Input id="243" points="215 1097" /> <Input id="254" points="148 1078" /> </Inputs> <Outputs> <Output id="251" points="214 1001" /> <Output id="253" points="154 1001" /> </Outputs> <Catalysts> <Catalyst id="252" points="182 1037" /> </Catalysts> <Properties> <displayName>dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="364" reactomeId="109343" points="301 979, 329 980, 357 980" position="329 980" lineWidth="1.0"> <Inputs> <Input id="251" points="283 978" /> <Input id="257" points="267 951" /> <Input id="258" points="281 1000" /> </Inputs> <Outputs> <Output id="255" points="385 983" /> <Output id="259" points="382 961" /> </Outputs> <Catalysts> <Catalyst id="256" points="326 956" /> </Catalysts> <Properties> <displayName>Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="365" reactomeId="109998" points="462 966, 453 927, 72 863, 70 347, 379 347, 391 393" position="453 927" lineWidth="1.0"> <Inputs> <Input id="255" /> </Inputs> <Outputs> <Output id="171" /> </Outputs> <Catalysts> <Catalyst id="241" points="556 929" /> </Catalysts> <Properties> <displayName>Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="373" reactomeId="71031" points="1276 779, 1277 801, 1277 838" position="1277 801" lineWidth="1.0"> <Inputs> <Input id="279" points="1276 756" /> <Input id="9330" points="1239 770" /> <Input id="9329" points="1302 774" /> </Inputs> <Outputs> <Output id="283" points="1277 875" /> <Output id="9331" points="1241 849" /> <Output id="282" points="1308 830" /> <Output id="9333" points="1315 859" /> </Outputs> <Catalysts> <Catalyst id="284" points="1247 800" /> </Catalysts> <Properties> <displayName>propionyl-CoA + CO2 + ATP &lt;=&gt; D-methylmalonyl-CoA + ADP + orthophosphate</displayName> <isChanged>true</isChanged> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="374" reactomeId="71020" points="1277 911, 1277 936, 1277 972" position="1277 936" lineWidth="1.0"> <Inputs> <Input id="283" /> </Inputs> <Outputs> <Output id="285" /> </Outputs> <Catalysts> <Catalyst id="286" points="1238 937" /> </Catalysts> <Properties> <displayName>D-methylmalonyl-CoA &lt;=&gt; L-methylmalonyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="375" reactomeId="71010" points="1277 1008, 1278 1030, 1278 1062" position="1278 1030" lineWidth="1.0"> <Inputs> <Input id="285" /> </Inputs> <Outputs> <Output id="272" /> </Outputs> <Catalysts> <Catalyst id="397" points="1238 1030" /> </Catalysts> <Properties> <displayName>MUT isomerises L-MM-CoA to SUCC-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3219" reactomeId="5695980" points="853 1041, 890 1041, 929 1042" position="890 1041" lineWidth="1.0"> <Inputs> <Input id="3220" points="808 1020" /> <Input id="5174" points="826 1048" /> </Inputs> <Outputs> <Output id="3222" points="972 1020" /> <Output id="5172" points="965 1048" /> </Outputs> <Catalysts> <Catalyst id="3224" points="890 1014" /> </Catalysts> <Properties> <displayName>ACAD10 dehydrogenates S-2MPDA-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="3225" reactomeId="5695989" points="1216 1136, 1254 1136, 1276 1169" position="1254 1136" lineWidth="1.0"> <Inputs> <Input id="3226" points="1177 1137" /> <Input id="5168" points="1200 1157" /> </Inputs> <Outputs> <Output id="3227" points="1302 1187" /> <Output id="5170" points="1273 1223" /> </Outputs> <Catalysts> <Catalyst id="3228" points="1333 1135" /> </Catalysts> <Properties> <displayName>ACAD11 dehydrogenates BH-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="7388" reactomeId="8874745" points="1192 616, 1192 576, 1192 533" position="1192 576" lineWidth="1.0"> <Inputs> <Input id="7389" points="1212 627" /> <Input id="197" points="1130 637" /> </Inputs> <Outputs> <Output id="7390" points="1212 523" /> <Output id="199" points="1130 526" /> </Outputs> <Catalysts> <Catalyst id="7391" points="1246 576" /> </Catalysts> <Properties> <displayName>ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="7937" reactomeId="8875013" points="168 689, 168 717, 168 741" position="168 717" lineWidth="1.0"> <Inputs> <Input id="7939" points="168 662" /> <Input id="9325" points="150 684" /> <Input id="7938" points="185 674" /> </Inputs> <Outputs> <Output id="213" points="204 729" /> <Output id="8009" points="145 754" /> <Output id="8011" points="170 766" /> </Outputs> <Catalysts> <Catalyst id="7940" points="144 717" /> </Catalysts> <Properties> <displayName>ACSM3,ACSM6 ligate CoA to BUT</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="9109" reactomeId="8933547" points="1217 1350, 1244 1351, 1279 1351" position="1244 1351" lineWidth="1.0"> <Inputs> <Input id="9110" points="1193 1343" /> <Input id="9260" points="1184 1383" /> </Inputs> <Outputs> <Output id="9124" points="1305 1379" /> <Output id="9116" points="1306 1332" /> </Outputs> <Catalysts> <Catalyst id="9112" points="1241 1308" /> </Catalysts> <Properties> <displayName>MCAT transfers Mal from Mal-CoA to NDUFAB1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="9154" reactomeId="8952873" points="463 400, 497 401, 528 402" position="497 401" lineWidth="1.0"> <Inputs> <Input id="171" points="431 409" /> <Input id="9157" points="437 386" /> <Input id="9159" points="442 363" /> </Inputs> <Outputs> <Output id="167" points="547 409" /> <Output id="9161" points="551 387" /> </Outputs> <Catalysts> <Catalyst id="9155" points="496 370" /> </Catalysts> <Properties> <displayName>MECR dimer reduces tdec2-CoA to DEC-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="9172" reactomeId="5696004" points="856 1168, 902 1168, 931 1169" position="902 1168" lineWidth="1.0"> <Inputs> <Input id="9173" points="800 1167" /> <Input id="9174" points="821 1143" /> <Input id="9182" points="836 1194" /> </Inputs> <Outputs> <Output id="9175" points="981 1168" /> <Output id="9178" points="924 1139" /> <Output id="9180" points="979 1133" /> </Outputs> <Catalysts> <Catalyst id="9176" points="902 1203" /> </Catalysts> <Properties> <displayName>ACSF2 ligates CoA-SH to MCFA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="9183" reactomeId="5690066" points="924 1266, 890 1266, 859 1266" position="890 1266" lineWidth="1.0"> <Inputs> <Input id="9184" points="969 1266" /> <Input id="9186" points="983 1303" /> </Inputs> <Outputs> <Output id="9187" points="824 1266" /> <Output id="9182" points="835 1230" /> <Output id="9359" points="821 1296" /> </Outputs> <Catalysts> <Catalyst id="9189" points="890 1303" /> </Catalysts> <Properties> <displayName>ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA</displayName> <isChanged>true</isChanged> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="9185" points="1023 1186, 1023 1242" position="1023 1214" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="9175" /> </Inputs> <Outputs> <Output id="9184" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="9188" points="772 1185, 776 1250" position="774 1217" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="9173" /> </Inputs> <Outputs> <Output id="9187" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="9201" reactomeId="5690043" points="1743 796, 1785 796, 1837 799" position="1785 796" lineWidth="1.0"> <Inputs> <Input id="9202" points="1722 767" /> <Input id="9203" points="1714 796" /> </Inputs> <Outputs> <Output id="9204" points="1895 798" /> <Output id="9205" points="1889 827" /> <Output id="9362" points="1872 768" /> </Outputs> <Catalysts> <Catalyst id="9206" points="1785 836" /> </Catalysts> <Activators> <Activator id="9207" points="1785 760" /> </Activators> <Properties> <displayName>Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="9226" reactomeId="8848250" points="1529 844, 1529 869, 1529 906" position="1529 869" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="9227" points="1529 815" /> <Input id="9229" points="1498 836" /> </Inputs> <Outputs> <Output id="9230" /> </Outputs> <Properties> <displayName>ACBD6 binds LCFA-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="9228" points="1577 798, 1617 798" position="1597 798" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="9227" /> </Inputs> <Outputs> <Output id="9203" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="9241" reactomeId="8848246" points="1651 1075, 1681 1075, 1724 1076" position="1681 1075" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="9242" points="1598 1087" /> <Input id="9243" points="1599 1064" /> </Inputs> <Outputs> <Output id="9244" /> </Outputs> <Properties> <displayName>DBI, ACBD7 bind MCFA-CoA and LCFA-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableInteraction id="9248" interactionType="Activate" points="855 907, 904 907" position="879 907" lineWidth="2.0"> <Inputs> <Input id="9246" /> </Inputs> <Outputs> <Output id="9247" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.RenderableInteraction id="9259" interactionType="Activate" points="1234 1080, 1160 1080, 1012 943" position="1160 1080" lineWidth="2.0"> <Inputs> <Input id="272" /> </Inputs> <Outputs> <Output id="9247" /> </Outputs> </org.gk.render.RenderableInteraction> </Edges> <Pathways /> </Process>
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No pathways have been reviewed or authored by Diagram of Mitochondrial Fatty Acid Beta-Oxidation and Diseases of mitochondrial beta oxidation (8979029)
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