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Details on Person UniProt:Q06323-2 PSME1
| Class:Id | ReferenceIsoform:8977574 |
|---|---|
| _chainChangeLog | chain:1-249 added on Fri February 17 2017 |
| _displayName | UniProt:Q06323-2 PSME1 |
| _timestamp | 2024-11-03 20:07:10 |
| chain | chain:1-249 |
| checksum | 5E27727E5A0B0AAB |
| comment | FUNCTION Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.SUBUNIT Heterodimer of PSME1 and PSME2, which forms a hexameric ring. PSME1 can form homoheptamers.INTERACTION By IFNG/IFN-gamma.SIMILARITY Belongs to the PA28 family. |
| created | [InstanceEdit:8964659] Weiser, JD |
| description | recommendedName: Proteasome activator complex subunit 1 alternativeName: 11S regulator complex subunit alpha shortName: REG-alpha alternativeName: Activator of multicatalytic protease subunit 1 alternativeName: Interferon gamma up-regulated I-5111 protein shortName: IGUP I-5111 alternativeName: Proteasome activator 28 subunit alpha shortName: PA28a shortName: PA28alpha |
| geneName | PSME1 IFI5111 |
| identifier | Q06323 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Direct protein sequencing Proteasome Proteomics identification Reference proteome |
| modified | [InstanceEdit:8987656] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9715482] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | PSME1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8962410] ENSEMBL:ENSG00000092010 PSME1 [Homo sapiens] |
| secondaryIdentifier | PSME1_HUMAN A6NJG9 H0YNE3 Q6IBM2 Q9UEF4 |
| sequenceLength | 249 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | Q06323-2 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q06323-2 PSME1 (8977574)
