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Details on Person UniProt:Q86YN1-1 DOLPP1
| Class:Id | ReferenceIsoform:8974243 |
|---|---|
| _chainChangeLog | chain:1-238 added on Fri February 17 2017 |
| _displayName | UniProt:Q86YN1-1 DOLPP1 |
| _timestamp | 2025-02-21 19:17:09 |
| chain | chain:1-238 |
| checksum | 3A9DD3383C61BE94 |
| comment | FUNCTION Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity).CATALYTIC ACTIVITY a di-trans,poly-cis-dolichyl diphosphate + H2O = a di-trans,poly-cis-dolichyl phosphate + phosphate + H(+)PATHWAY Protein modification; protein glycosylation.SUBCELLULAR LOCATION Belongs to the dolichyldiphosphatase family. |
| created | [InstanceEdit:8964659] Weiser, JD |
| description | recommendedName: Dolichyldiphosphatase 1 ecNumber: 3.6.1.43 alternativeName: Dolichyl pyrophosphate phosphatase 1 |
| geneName | DOLPP1 LSFR2 |
| identifier | Q86YN1 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Endoplasmic reticulum Hydrolase Membrane Proteomics identification Reference proteome Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | DOLPP1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8962368] ENSEMBL:ENSG00000167130 DOLPP1 [Homo sapiens] |
| secondaryIdentifier | DOPP1_HUMAN A8K3U8 B0QZG4 Q96GF8 Q9Y3G1 |
| sequenceLength | 238 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | Q86YN1-1 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q86YN1-1 DOLPP1 (8974243)
