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Details on Person UniProt:O22040-1 ANP1

Class:IdReferenceIsoform:8971332
_chainChangeLogchain:1-666 added on Fri February 17 2017
_displayNameUniProt:O22040-1 ANP1
_timestamp2025-02-21 20:06:21
chainchain:1-666
checksum588C6339CDC58C18
commentFUNCTION May be involved in an oxidative stress-mediated signaling cascade that phosphorylates downstream MAP kinases MPK3 and MPK6. May suppress auxin signaling that promotes cell cycle. Functionally redundant to ANP2 and ANP3 in the positive regulation of cytokinesis.CATALYTIC ACTIVITY L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)CATALYTIC ACTIVITY L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)ALTERNATIVE PRODUCTS Expressed in roots, inflorescence stems, flower buds and flowers. Low amount in rosette and cauline leaves.MISCELLANEOUS The protein kinase activity of isoform 1S is higher than that of isoform 1L.SIMILARITY Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
created[InstanceEdit:8964659] Weiser, JD
descriptionrecommendedName: Mitogen-activated protein kinase kinase kinase ANP1 ecNumber: 2.7.11.25 alternativeName: Arabidopsis NPK1-related kinase 1
geneNameANP1
At1g09000
F7G19.13
identifierO22040
isoformParent
isSequenceChangedFALSE
keywordAlternative splicing
ATP-binding
Coiled coil
Isopeptide bond
Kinase
Nucleotide-binding
Reference proteome
Serine/threonine-protein kinase
Transferase
Ubl conjugation
modified[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9939033] Weiser, Joel, 2025-02-21
nameANP1
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierANP1_ARATH
O04030
O22039
Q8GZ05
sequenceLength666
species[Species:170905] Arabidopsis thaliana
variantIdentifierO22040-1
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No pathways have been reviewed or authored by UniProt:O22040-1 ANP1 (8971332)