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Details on Person UniProt:Q9S7I8-2 CDC20-2
| Class:Id | ReferenceIsoform:8970416 |
|---|---|
| _chainChangeLog | chain:1-447 added on Fri February 17 2017 |
| _displayName | UniProt:Q9S7I8-2 CDC20-2 |
| _timestamp | 2023-11-03 15:25:35 |
| chain | chain:1-447 |
| checksum | 863312116D03B7AD |
| comment | FUNCTION Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.PATHWAY Protein modification; protein ubiquitination.SUBUNIT The APC/C is composed of at least 11 subunits that stay tightly associated throughout the cell cycle (By similarity). Interacts with APC10, FZR1, FZR2, FZR3. Part of the mitotic checkpoint complex (MCC); interacts with MAD2, BUB3.1, BUBR1 and BUB1. Binds to cyclins CYCA1-2, CYCB2-1 and CYCB2-2.SUBCELLULAR LOCATION Expressed in meristems and organ primordia. Present in flowers, leaves, stems and roots.INDUCTION Expression starts to rise in the S-phase and peaks in the M-phase with a non-negligible basic expression level also in the other cell cycle phases.DISRUPTION PHENOTYPE Delay in plant development due to reduced cell number and male sterility.SIMILARITY Belongs to the WD repeat CDC20/Fizzy family. |
| created | [InstanceEdit:8964659] Weiser, JD |
| description | recommendedName: Cell division cycle 20.2, cofactor of APC complex shortName: AtCDC20.2 |
| geneName | CDC20-2 CDC20_1 At4g33260 F17M5.20 |
| identifier | Q9S7I8 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Cell cycle Cell division Mitosis Nucleus Reference proteome Repeat Ubl conjugation pathway WD repeat |
| modified | [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | CDC20-2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | CDC22_ARATH F4JW04 |
| sequenceLength | 447 |
| species | [Species:170905] Arabidopsis thaliana |
| variantIdentifier | Q9S7I8-2 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9S7I8-2 CDC20-2 (8970416)
