Reactome: A Curated Pathway Database
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Query author contributions in Reactome

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Details on Person UniProt:Q8NFW1-3 COL22A1

Class:IdReferenceIsoform:8969131
_chainChangeLogsignal peptide:1-27 added on Fri February 17 2017;chain:28-1626 added on Fri February 17 2017
_displayNameUniProt:Q8NFW1-3 COL22A1
_timestamp2024-08-09 18:41:37
chainsignal peptide:1-27
chain:28-1626
checksum91018ABA2DD670EC
commentFUNCTION Acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.SUBCELLULAR LOCATION Restrictive expression is observed at tissue junctions such as the myotendinous junction in skeletal and heart muscle, the articular cartilage-synovial fluid junction, or the border between the anagen hair follicle and the dermis in the skin. It is deposited in the basement membrane zone of the myotendinous junction and the hair follicle and associated with the extrafibrillar matrix in cartilage.SIMILARITY Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
created[InstanceEdit:8964659] Weiser, JD
descriptionrecommendedName: Collagen alpha-1(XXII) chain
geneNameCOL22A1
identifierQ8NFW1
isoformParent
isSequenceChangedFALSE
keywordAlternative splicing
Collagen
Cytoplasm
Extracellular matrix
Glycoprotein
Proteomics identification
Reference proteome
Repeat
Secreted
Signal
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9917590] Weiser, Joel, 2024-08-09
nameCOL22A1
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9001089] ENSEMBL:ENSG00000169436 COL22A1 [Homo sapiens]
secondaryIdentifierCOMA1_HUMAN
B7ZMH0
C9K0G4
Q8IVT9
sequenceLength1626
species[Species:48887] Homo sapiens
variantIdentifierQ8NFW1-3
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No pathways have been reviewed or authored by UniProt:Q8NFW1-3 COL22A1 (8969131)