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Details on Person UniProt:P05386-1 RPLP1
| Class:Id | ReferenceIsoform:8965799 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Fri February 17 2017;chain:2-114 added on Fri February 17 2017;initiator methionine:1 for 8965799 removed on Fri Nov 03 2023;initiator methionine: for 8965799 added on Fri Nov 03 2023;initiator methionine: for 8965799 removed on Fri Aug 15 2025;initiator methionine:1 for 8965799 added on Fri Aug 15 2025 |
| _displayName | UniProt:P05386-1 RPLP1 |
| _timestamp | 2025-08-15 21:18:26 |
| chain | initiator methionine:1 chain:2-114 |
| checksum | 4C282AB8DCA079C8 |
| comment | FUNCTION Plays an important role in the elongation step of protein synthesis.SUBUNIT Heterodimer with RPLP2 at the lateral ribosomal stalk of the large ribosomal subunit.INTERACTION Ubiquitinated at Lys-92 and Lys-93 by RNF14 and RNF25 in response to ribosome collisions (ribosome stalling).SIMILARITY Belongs to the eukaryotic ribosomal protein P1/P2 family. |
| created | [InstanceEdit:8964659] Weiser, JD |
| description | recommendedName: fullName evidence="6"Large ribosomal subunit protein P1 alternativeName: 60S acidic ribosomal protein P1 |
| geneName | RPLP1 RRP1 |
| identifier | P05386 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Alternative splicing Isopeptide bond Phosphoprotein Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | RPLP1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8958129] ENSEMBL:ENSG00000137818 RPLP1 [Homo sapiens] |
| secondaryIdentifier | RLA1_HUMAN A6NIB2 |
| sequenceLength | 114 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | P05386-1 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P05386-1 RPLP1 (8965799)
