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Details on Person The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CCNA2 gene promoter

Class:Id	Reaction:8964580
_displayName	The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CCNA2 gene promoter
_doRelease	TRUE
_timestamp	2017-02-28 16:48:32
authored	[InstanceEdit:1363332] Orlic-Milacic, Marija, 2011-06-14
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8964581] Orlic-Milacic, Marija, 2017-02-17
edited	[InstanceEdit:8961898] Orlic-Milacic, Marija, 2017-02-06
inferredFrom	[Reaction:8978970] The complex of Hdac1, Rbl1 and E2f4 or Hdac1, Rbl2 and E2f4 or E2f5 binds Ccna2 gene promoter [Mus musculus]
input	[DefinedSet:8964549] HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8964583] CCNA2 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1362298] E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
modified	[InstanceEdit:8978975] Orlic-Milacic, Marija, 2017-02-20 [InstanceEdit:8980637] Orlic-Milacic, Marija, 2017-02-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds CCNA2 gene promoter
output	[Complex:8964582] HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:CCNA2 gene [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:1227671] Recruitment of HDAC1 by p107 (RBL1) [Homo sapiens] [Reaction:1227670] Recruitment of HDAC1 by p130 (RBL2) [Homo sapiens]
releaseDate	2011-09-20
reviewed	[InstanceEdit:1538129] MacPherson, D, 2011-08-25
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8964584] R-HSA-8964580.2
summation	[Summation:8964578] In G0 and early G1, complexes containing p130 (RBL2) and p10...
(hasEvent)	[Pathway:1362300] Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:8964588] CCNA2 gene expression is inhibited by RBL1 and RBL2 [Homo sapiens]
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