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Details on Person DREAM complex binds the CDC6 gene promoter

Class:Id	Reaction:8964498
_displayName	DREAM complex binds the CDC6 gene promoter
_doRelease	TRUE
_timestamp	2017-02-28 16:48:29
authored	[InstanceEdit:1363332] Orlic-Milacic, Marija, 2011-06-14
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8964497] Orlic-Milacic, Marija, 2017-02-17
edited	[InstanceEdit:8961898] Orlic-Milacic, Marija, 2017-02-06
input	[Complex:1362264] DREAM complex [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8961618] CDC6 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1362256] Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
modified	[InstanceEdit:8980637] Orlic-Milacic, Marija, 2017-02-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	DREAM complex binds the CDC6 gene promoter
output	[Complex:8964499] DREAM complex:CDC6 gene [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:1362261] p130 (RBL2) associates with MuvB to form DREAM complex [Homo sapiens] [Reaction:1362270] Phosphorylation of LIN52 component of MuvB by DYRK1A [Homo sapiens]
releaseDate	2011-09-20
reviewed	[InstanceEdit:1538129] MacPherson, D, 2011-08-25
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8964500] R-HSA-8964498.2
summation	[Summation:8964496] The DREAM complex binds the promoter of the CDC6 gene (Litov...
(hasEvent)	[Pathway:1362277] Transcription of E2F targets under negative control by DREAM complex [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:8961619] CDC6 gene expression is stimulated by E2F1 and repressed by the DREAM complex [Homo sapiens]
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No pathways have been reviewed or authored by DREAM complex binds the CDC6 gene promoter (8964498)