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Details on Person Diagram of Lysine catabolism

Class:IdPathwayDiagram:8964214
_displayNameDiagram of Lysine catabolism
_timestamp2025-07-11 17:15:00
created[InstanceEdit:8964217] Jassal, Bijay, 2017-02-16
height891
modified[InstanceEdit:9640340] D'Eustachio, Peter, 2019-03-25
[InstanceEdit:9858341] Stephan, Ralf, 2024-01-12
[InstanceEdit:9858583] Stephan, Ralf, 2024-01-13
[InstanceEdit:9858593] Stephan, Ralf, 2024-01-13
[InstanceEdit:9858599] Stephan, Ralf, 2024-01-13
[InstanceEdit:9859575] Stephan, Ralf, 2024-01-21
[InstanceEdit:9859623] Stephan, Ralf, 2024-01-23
[InstanceEdit:9907332] Stephan, Ralf, 2024-04-06
[InstanceEdit:9907757] Stephan, Ralf, 2024-04-17
[InstanceEdit:9925993] D'Eustachio, Peter, 2024-10-29
[InstanceEdit:9929230] D'Eustachio, Peter, 2024-11-22
[InstanceEdit:9938950] D'Eustachio, Peter, 2025-02-20
[InstanceEdit:9960426] D'Eustachio, Peter, 2025-07-11
representedPathway[Pathway:71064] Lysine catabolism [Homo sapiens]
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</Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="133" reactomeId="6788611" points="349 710, 412 710, 467 710" position="412 710" lineWidth="1.0"> <Inputs> <Input id="134" points="341 730" /> <Input id="135" points="303 710" /> </Inputs> <Outputs> <Output id="137" points="522 710" /> <Output id="136" points="476 734" /> <Output id="709" points="483 686" /> </Outputs> <Catalysts> <Catalyst id="138" points="411 679" /> </Catalysts> <Properties> <displayName>HYKK phosphorylates 5HLYS</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="139" reactomeId="5696408" points="616 709, 661 709, 728 709" position="661 709" lineWidth="1.0"> <Inputs> <Input id="137" points="574 709" /> <Input id="140" points="601 728" /> </Inputs> <Outputs> <Output id="31" points="726 547" /> <Output id="710" points="756 690" /> <Output id="141" points="756 728" /> </Outputs> <Catalysts> <Catalyst id="143" points="661 681" /> </Catalysts> <Properties> <displayName>PXLP-K278-PHYKPL tetramer hydrolyses 5PHL</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="164" reactomeId="70941" points="836 527, 896 527, 937 527" position="896 527" lineWidth="1.0"> <Inputs> <Input id="31" points="760 527" /> <Input id="165" points="814 555" /> <Input id="168" points="805 498" /> </Inputs> <Outputs> <Output id="166" points="1011 527" /> <Output id="171" stoichiometry="2" points="974 497" /> <Output id="169" points="966 555" /> </Outputs> <Catalysts> <Catalyst id="167" points="896 493" /> </Catalysts> <Properties> <displayName>alpha-aminoadipoate semialdehyde + NAD+ =&gt; alpha-aminoadipate + NADH + H+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="192" reactomeId="70952" points="1109 527, 1160 527, 1213 527" position="1160 527" lineWidth="1.0"> <Inputs> <Input id="166" points="1060 527" /> <Input id="195" points="1091 494" /> </Inputs> <Outputs> <Output id="193" points="1269 527" /> <Output id="196" points="1238 497" /> </Outputs> <Catalysts> <Catalyst id="194" points="1160 553" /> </Catalysts> <Properties> <displayName>alpha-aminoadipate + alpha-ketoglutarate &lt;=&gt; alpha-ketoadipate + glutamate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="197" reactomeId="508561" points="1245 637, 1160 637, 1117 637" position="1160 637" lineWidth="1.0"> <Inputs> <Input id="193" points="1293 546" /> <Input id="196" points="1249 497" /> </Inputs> <Outputs> <Output id="166" points="1046 546" /> <Output id="195" points="1087 494" /> </Outputs> <Catalysts> <Catalyst id="194" points="1160 595" /> </Catalysts> <Properties> <displayName>alpha-ketoadipate + glutamate &lt;=&gt; alpha-aminoadipate + alpha-ketoglutarate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="242" reactomeId="372480" points="1355 387, 1354 387, 1355 387" position="1354 387" lineWidth="1.0"> <Inputs> <Input id="195" points="1108 469" /> <Input id="243" points="1319 256" /> </Inputs> <Outputs> <Output id="244" points="1396 257" /> <Output id="193" points="1306 509" /> </Outputs> <Catalysts> <Catalyst id="245" points="1396 387" /> </Catalysts> <Properties> <displayName>2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] &lt;=&gt; 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix]</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="295" reactomeId="71046" points="1912 527, 1965 527, 2021 527" position="1965 527" lineWidth="1.0"> <Inputs> <Input id="268" points="1845 527" /> <Input id="296" points="1874 496" /> <Input id="896" stoichiometry="2" points="1879 553" /> </Inputs> <Outputs> <Output id="297" points="2050 506" /> <Output id="298" points="2064 527" /> <Output id="460" points="2056 554" /> </Outputs> <Catalysts> <Catalyst id="299" points="1965 476" /> </Catalysts> <Properties> <displayName>glutaryl-CoA + FAD =&gt; crotonyl-CoA + FADH2 + CO2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="478" reactomeId="9858321" points="1403 554, 1428 554, 1456 554" position="1428 554" lineWidth="1.0"> <Inputs> <Input id="479" points="1390 495" /> <Input id="193" points="1333 534" /> <Input id="482" points="1376 573" /> </Inputs> <Outputs> <Output id="480" points="1501 555" /> <Output id="269" points="1496 601" /> </Outputs> <Catalysts> <Catalyst id="455" points="1523 505" /> </Catalysts> <Properties> <displayName>DHTKD1 dimer decarboxylates 2-OA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="483" reactomeId="9858590" points="1651 557, 1684 557, 1726 555" position="1684 557" lineWidth="1.0"> <Inputs> <Input id="484" points="1622 605" /> <Input id="480" points="1614 557" /> <Input id="967" points="1668 607" /> </Inputs> <Outputs> <Output id="485" points="1732 497" /> <Output id="268" points="1784 535" /> </Outputs> <Catalysts> <Catalyst id="455" points="1583 505" /> </Catalysts> <Properties> <displayName>DLST transfers glutaryl to CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="486" reactomeId="9858589" points="1590 421, 1555 421, 1521 422" position="1555 421" lineWidth="1.0"> <Inputs> <Input id="485" points="1683 456" /> <Input id="491" points="1643 417" /> </Inputs> <Outputs> <Output id="479" points="1430 456" /> <Output id="488" points="1496 448" /> <Output id="489" points="1458 422" /> </Outputs> <Catalysts> <Catalyst id="455" points="1554 466" /> </Catalysts> <Properties> <displayName>DLD dimer dehydrogenates dihydrolipoyl</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="980" reactomeId="9960428" points="725 276, 725 320, 725 510" position="725 320" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="968" /> </Inputs> <Outputs> <Output id="31" /> </Outputs> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process>
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No pathways have been reviewed or authored by Diagram of Lysine catabolism (8964214)
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